Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CASR | P41180 | 1/20 | 0.32 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.30 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.30 |
| ▸ | SLC7A5 | Q01650 | 5/20 | 0.30 |
| ▸ | TLR4 | O00206 | 1/20 | 0.30 |
| ▸ | TLR2 | O60603 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9478805 | 0.81 | ALDH1A1 (0.65) | ALDH1A1NPC1RAB9AMAPTALOX15 | |
| SCHEMBL4865335 | 0.77 | SRD5A2 (0.42) | MAPTALOX15SLC7A5 | |
| SCHEMBL19084670 | 0.76 | ALDH1A3 (0.50) | ALDH1A1NPC1RAB9AMAPTALOX15 | |
| SCHEMBL8466535 | 0.75 | SLC7A5 (0.40) | ALDH1A1NPC1RAB9AALOX15KMT2A | |
| SCHEMBL244830 | 0.74 | TDP1 (0.59) | ALDH1A1MAPTALOX15TDP1KMT2A | |
| SCHEMBL267779 | 0.74 | TDP1 (0.59) | ALDH1A1MAPTALOX15TDP1KMT2A | |
| SCHEMBL3291158 | 0.74 | SLC6A4 (0.39) | ALDH1A1MAPTALOX15CASRSLC7A5 | |
| SCHEMBL6260317 | 0.74 | TDP1 (0.59) | ALDH1A1MAPTALOX15TDP1KMT2A | |
| SCHEMBL8625767 | 0.73 | ALDH1A3 (0.50) | ALDH1A1RAB9AMAPTKMT2ALTB4R | |
| SCHEMBL3294031 | 0.73 | NPSR1 (0.41) | ALDH1A1KMT2ASLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5219710-A | Optical waveguides; change refractive index upon exposure to actinic radiation; heat resistant | ALLIED-SIGNAL INC. (US) | 1993-06-15 | — | — | US | claimed |
| WO-1993011169-A1 | POLYMERIC NITRONES HAVING A STYRENE-DERIVED BACKBONE CHAIN | ALLIED-SIGNAL INC. (US) | 1993-06-10 | — | — | WO | disclosed |