Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2152818 | 0.80 | FBP1 (0.49) | NPC1RAB9AALDH1A1LMNATSHR | |
| SCHEMBL9477157 | 0.76 | ALDH1A1 (0.42) | NPC1RAB9AMAPTALDH1A1ALOX15 | |
| SCHEMBL7921065 | 0.76 | ALDH1A1 (0.40) | MAPTALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL6154484 | 0.76 | PTGS2 (0.51) | NPC1RAB9AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL15216491 | 0.74 | FBP1 (0.44) | NPC1RAB9AALDH1A1GAASMN1; SMN2 | |
| SCHEMBL28552488 | 0.74 | FBP1 (0.44) | NPC1RAB9AALDH1A1GAASMN1; SMN2 | |
| SCHEMBL8002732 | 0.73 | MAPT (0.49) | MAPTALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL6154192 | 0.73 | AHR (0.45) | NPC1RAB9AMAPTALDH1A1LMNA | |
| SCHEMBL5671601 | 0.73 | POLB (0.40) | ALDH1A3MAPTALDH1A1LMNAGAA | |
| SCHEMBL8039808 | 0.72 | ALDH1A1 (0.46) | NPC1MAPTALDH1A1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170189429-A1 | Treating Arrhythmia with Mitochondrial-Targeted Antioxidants | RHODE ISLAND HOSPITAL | 2017-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170189429-A1 | Treating Arrhythmia with Mitochondrial-Targeted Antioxidants | COQ8A, SQOR, COQ8B | ALDH1A3 446/4885NPC1 1157/4885RAB9A 957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.