Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 3/20 | 0.33 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.33 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.33 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.33 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
| ▸ | PRCP | P42785 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9475710 | 0.84 | ABCC9 (0.41) | ABCC9ABCC8KCNJ11KCNJ8CHRM1 | |
| SCHEMBL9475069 | 0.82 | ABCC9 (0.52) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9475563 | 0.80 | CHRM1 (0.31) | ABCC9ABCC8KCNJ11KCNJ8CHRM1 | |
| SCHEMBL9475319 | 0.80 | ABCC9 (0.31) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL8796317 | 0.80 | ABCC9 (0.42) | GPR3ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9476803 | 0.79 | ABCC9 (0.32) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9477112 | 0.78 | ALOX5 (0.39) | ABL1 | |
| SCHEMBL9476478 | 0.77 | ABCC9 (0.32) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9475647 | 0.77 | CBFB (0.43) | GPR3CHRM1BACE1CES1ABL1 | |
| SCHEMBL9476372 | 0.77 | L3MBTL1 (0.36) | GPR3CHRM1CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477789-A1 | 1,3-Benzoxazine derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1992-04-01 | — | — | EP | claimed |
| US-5270308-A | Hypotensives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-12-14 | — | — | US | disclosed |
| EP-0477789-A1 | 1,3-Benzoxazine derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1992-04-01 | — | — | EP | disclosed |