Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSPO | P30536 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9372436 | 0.89 | NLRP3 (0.43) | HPGDSMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL769278 | 0.78 | GAA (0.48) | HPGDSMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL9376548 | 0.77 | NLRP3 (0.39) | SMN1; SMN2KMT2AMEN1LMNANLRP3 | |
| SCHEMBL9374168 | 0.75 | NLRP3 (0.40) | HPGDSMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL9369583 | 0.75 | NLRP3 (0.40) | HPGDSMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL9373260 | 0.75 | ITGB1 (0.39) | SMN1; SMN2NLRP3ALDH1A1 | |
| SCHEMBL9372688 | 0.74 | F2 (0.40) | HPGDSMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL2167246 | 0.73 | NLRP3 (0.51) | HPGDSMN1; SMN2KMT2ALMNANLRP3 | |
| SCHEMBL9368665 | 0.72 | PIN1 (0.47) | SMN1; SMN2KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL9368524 | 0.72 | NLRP3 (0.37) | HPGDSMN1; SMN2NLRP3ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5186737-A | Herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1993-02-16 | — | — | US | disclosed |
| US-5045560-A | Insecticides, nematocides, fungicides, herbicides, human and veterinary medicine | BAYER AKTIENGESELLSCHAFT (DE) | 1991-09-03 | — | — | US | disclosed |