Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 2/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | HBB | P68871 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NT5E | P21589 | 2/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30357699 | 0.87 | LMNA (0.48) | ALDH1A1HSD17B10TDP1LMNACASP6 | |
| SCHEMBL2263563 | 0.87 | LMNA (0.48) | ALDH1A1HSD17B10TDP1LMNACASP6 | |
| SCHEMBL1802953 | 0.81 | LMNA (0.67) | ALDH1A1CYP3A4HSD17B10TDP1LMNA | |
| SCHEMBL30615201 | 0.80 | LMNA (0.46) | ALDH1A1HSD17B10TDP1LMNACASP6 | |
| SCHEMBL2263247 | 0.80 | LMNA (0.46) | ALDH1A1HSD17B10TDP1LMNACASP6 | |
| SCHEMBL158630 | 0.79 | NT5E (0.66) | ALDH1A1CYP3A4HSD17B10TDP1ALOX15 | |
| SCHEMBL8784773 | 0.79 | ALDH1A1 (0.46) | ALDH1A1CYP3A4HSD17B10TDP1ALOX15 | |
| SCHEMBL29670171 | 0.79 | NT5E (0.66) | ALDH1A1CYP3A4HSD17B10TDP1ALOX15 | |
| Potassium Ion SCHEMBL9110795 | 0.79 | ALDH1A1 (0.46) | ALDH1A1CYP3A4HSD17B10TDP1ALOX15 | |
| SCHEMBL10484185 | 0.79 | AKR1C3 (0.49) | ALDH1A1CYP3A4HSD17B10TDP1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110009389-A1 | IMIDAZOLE DERIVATIVE, THEIR PRODUCTION AND USE | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-01-13 | — | — | US | disclosed |
| US-20070004736-A1 | Imidazole derivative, process for producing the same, and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-04 | — | — | US | disclosed |
| EP-1564213-A1 | IMIDAZOLE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE | Takeda Pharmaceutical Company Limited (JP) | 2005-08-17 | — | — | EP | disclosed |
| EP-0501415-B1 | Monoazo compounds and method for dyeing or printing fiber materials using the same | SUMITOMO CHEMICAL CO (JP) | 1999-05-26 | — | — | EP | disclosed |
| US-5606092-A | COLORFAST RED COLOR; FIBER REACTIVE DYE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-02-25 | — | — | US | disclosed |
| US-5488098-A | FOR COTTON, POLYAMIDES, POLYURETHANES, LEATHER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-01-30 | — | — | US | disclosed |
| EP-0501415-A1 | Monoazo compounds and method for dyeing or printing fiber materials using the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-09-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004736-A1 | Imidazole derivative, process for producing the same, and use | HRH4, F2, HRH2 | ALDH1A1 2246/4885CYP3A4 29/4885HSD17B10 821/4885 |
| US-20110009389-A1 | IMIDAZOLE DERIVATIVE, THEIR PRODUCTION AND USE | F2, H1-3, CYC1 | ALDH1A1 2316/4885CYP3A4 40/4885HSD17B10 888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.