SCHEMBL10484185

SCHEMBL10484185

CS(=O)(=O)c1ccc2cc(N)ccc2c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 2/20 0.49
AKR1C2 P52895 2/20 0.49
G6PD P11413 1/20 0.48
IDE P14735 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.47
ALDH1A1 P00352 3/20 0.46
CYP3A4 P08684 3/20 0.46
HSD17B10 Q99714 2/20 0.46
ALOX15 P16050 1/20 0.45
CASP1 P29466 1/20 0.45
CASP7 P55210 1/20 0.45
HBB P68871 1/20 0.45
HIF1A Q16665 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
ATM Q13315 1/20 0.45
LMNA P02545 2/20 0.44
KDM4E B2RXH2 1/20 0.43
MEN1 O00255 1/20 0.43
MAPT P10636 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12508320 0.87 AKR1C3 (0.58) AKR1C3AKR1C2G6PDIDEL3MBTL1
SCHEMBL1802953 0.81 LMNA (0.67) ALDH1A1CYP3A4HSD17B10TDP1LMNA
SCHEMBL13203351 0.80 AKR1C3 (0.52) AKR1C3AKR1C2G6PDIDEL3MBTL1
Potassium Ion SCHEMBL9110795 0.79 ALDH1A1 (0.46) ALDH1A1CYP3A4HSD17B10ALOX15CASP1
SCHEMBL948147 0.79 ALDH1A1 (0.46) ALDH1A1CYP3A4HSD17B10ALOX15CASP1
SCHEMBL158630 0.79 NT5E (0.66) ALDH1A1CYP3A4HSD17B10ALOX15CASP1
SCHEMBL29670171 0.79 NT5E (0.66) ALDH1A1CYP3A4HSD17B10ALOX15CASP1
SCHEMBL8784773 0.79 ALDH1A1 (0.46) ALDH1A1CYP3A4HSD17B10ALOX15CASP1
SCHEMBL9404993 0.79 L3MBTL1 (0.68) L3MBTL1ALDH1A1CYP3A4HSD17B10TDP1
SCHEMBL6530359 0.79 HTR6 (0.42) L3MBTL1ALDH1A1CYP3A4HSD17B10ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4874848-A FOR DYEING WOOL, LEATHER, POLYAMIDES BLACK OR BROWN CIBA-GEIGY CORPORATION (US) 1989-10-17 US disclosed
US-4874849-A FOR DYEING WOOL, POLYAMIDES, LEATHER ORANGE OR BROWN CIBA-GEIGY CORPORATION (US) 1989-10-17 US disclosed
EP-0148120-B1 ASYMMETRICAL 1:2 CHROMIUM COMPLEX DYES CIBA-GEIGY AG (CH) 1988-11-23 EP disclosed
EP-0148121-B1 ASYMMETRICAL 1:2 CHROMIUM COMPLEX DYES CIBA-GEIGY AG (CH) 1988-11-09 EP disclosed
EP-0150676-B1 1:2 CHROMIUM COMPLEX DYES CIBA-GEIGY AG (CH) 1988-10-12 EP disclosed
EP-0151369-B1 ASYMMETRICAL 1:2 CHROME COMPLEXES CONTAINING AN AZO COMPOUND AND AN AZOMETHINE COMPOUND CIBA-GEIGY AG (CH) 1987-09-09 EP disclosed
US-4661587-A Bis 1:2 chromium complexes of disazo and azo or azomethine dyes CIBA-GEIGY CORPORATION (US) 1987-04-28 US disclosed
US-4652631-A LEATHER, WOOL, POLYAMIDES CIBA-GEIGY CORPORATION (US) 1987-03-24 US disclosed
US-4650859-A WOOL,POLYAMIDES, LEATHER CIBA-GEIGY CORPORATION (US) 1987-03-17 US disclosed
US-4625017-A LEATHER, COLORFASTNESS CIBA-GEIGY CORPORATION (US) 1986-11-25 US disclosed
EP-0079858-B1 AZO DYESTUFFS, METAL COMPLEXES THEREOF, THEIR PREPARATION AND USE CIBA-GEIGY AG (CH) 1985-12-27 EP disclosed
EP-0151369-A2 Asymmetrical 1:2 chrome complexes containing an azo compound and an azomethine compound CIBA-GEIGY AG (CH) 1985-08-14 EP disclosed
EP-0150676-A2 1:2 Chromium complex dyes CIBA-GEIGY AG (CH) 1985-08-07 EP disclosed
EP-0148120-A2 Asymmetrical 1:2 chromium complex dyes CIBA-GEIGY AG (CH) 1985-07-10 EP disclosed
EP-0148121-A2 Asymmetrical 1:2 chromium complex dyes CIBA-GEIGY AG (CH) 1985-07-10 EP disclosed
EP-0082117-B1 CHROMIUM COMPLEXES OF POLYAZO DYESTUFFS CIBA-GEIGY AG (CH) 1985-04-10 EP disclosed
US-4502860-A WOOL, POLYAMIDES, LEATHER CIBA-GEIGY CORPORATION (US) 1985-03-05 US disclosed
EP-0100297-A1 Bis-1:2-chromium complexes of disazo dyestuffs, their preparation and their use CIBA-GEIGY AG (CH) 1984-02-08 EP disclosed
EP-0082117-A1 Chromium complexes of polyazo dyestuffs CIBA-GEIGY AG (CH) 1983-06-22 EP disclosed
EP-0079858-A1 Azo dyestuffs, metal complexes thereof, their preparation and use CIBA-GEIGY AG (CH) 1983-05-25 EP disclosed