Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | HBB | P68871 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NT5E | P21589 | 2/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8784773 | 0.96 | ALDH1A1 (0.46) | ALDH1A1CYP3A4HSD17B10TDP1ALOX15 | |
| SCHEMBL30118452 | 0.90 | CYP3A4 (0.45) | ALDH1A1CYP3A4HSD17B10TDP1ALOX15 | |
| SCHEMBL4949497 | 0.90 | CYP3A4 (0.45) | ALDH1A1CYP3A4HSD17B10TDP1ALOX15 | |
| SCHEMBL28583716 | 0.88 | ALDH1A1 (0.43) | ALDH1A1CYP3A4HSD17B10TDP1ALOX15 | |
| Potassium Ion SCHEMBL29381494 | 0.87 | LMNA (0.50) | TDP1LMNAKMT2ACASP6TSHR | |
| Potassium Ion SCHEMBL1416019 | 0.87 | LMNA (0.50) | TDP1LMNAKMT2ACASP6TSHR | |
| SCHEMBL305422 | 0.82 | LMNA (0.56) | TDP1LMNAKMT2ACASP6PTPN11 | |
| Lithium Ion SCHEMBL3824799 | 0.82 | LMNA (0.50) | TDP1LMNAKMT2ACASP6TSHR | |
| SCHEMBL1802953 | 0.81 | LMNA (0.67) | ALDH1A1CYP3A4HSD17B10TDP1LMNA | |
| Potassium Ion SCHEMBL3825260 | 0.80 | LMNA (0.48) | TDP1LMNAKMT2ACASP6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113371942-A | Low-cost municipal sewage treatment method | 南京辉普环境工程有限公司 | 2021-09-10 | — | — | CN | claimed |
| CN-116283897-A | Compound and application of compound in solar cell | 西安隆基乐叶光伏科技有限公司 | 2023-06-23 | — | — | CN | disclosed |
| WO-2023109035-A1 | COMPOUND AND USE THEREOF IN SOLAR CELL | 西安隆基乐叶光伏科技有限公司 | 2023-06-22 | — | — | WO | disclosed |
| CN-113371942-A | Low-cost municipal sewage treatment method | 南京辉普环境工程有限公司 | 2021-09-10 | — | — | CN | disclosed |
| EP-0634013-A1 | A NICOTINE AND/OR NICOTINE METABOLITE DETECTION SYSTEM. | DYNAGEN INC (US) | 1995-01-18 | — | — | EP | disclosed |
| WO-1993020438-A1 | A NICOTINE AND/OR NICOTINE METABOLITE DETECTION SYSTEM | DYNAGEN, INC. (US) | 1993-10-14 | — | — | WO | disclosed |