Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAM | P19021 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL94815 | 1.00 | PAM (0.54) | PAMSIGMAR1IDO1MAOBHTR2A | |
| SCHEMBL95441 | 0.86 | PAM (0.50) | PAMSIGMAR1IDO1MAOBHTR2A | |
| SCHEMBL95442 | 0.86 | PAM (0.50) | PAMSIGMAR1IDO1MAOBHTR2A | |
| SCHEMBL7939387 | 0.85 | IDO1 (0.56) | PAMSIGMAR1IDO1MAOBHTR2A | |
| SCHEMBL10430031 | 0.85 | IDO1 (0.56) | PAMSIGMAR1IDO1MAOBHTR2A | |
| SCHEMBL7568412 | 0.85 | IDO1 (0.56) | PAMSIGMAR1IDO1MAOBHTR2A | |
| SCHEMBL95781 | 0.85 | PAM (0.48) | PAMSIGMAR1IDO1MAOBHTR2A | |
| SCHEMBL95782 | 0.85 | PAM (0.48) | PAMSIGMAR1IDO1MAOBHTR2A | |
| SCHEMBL2399949 | 0.84 | PAM (0.52) | PAMSIGMAR1IDO1MAOBHTR2A | |
| SCHEMBL97315 | 0.84 | PAM (0.52) | PAMSIGMAR1IDO1MAOBHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219477-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2023-08-02 | — | — | EP | disclosed |
| US-20220089553-A1 | HIGH-PURITY THERMOSTABLE CRYSTAL FORM OF SUBSTITUTED 3-ISOXAZOLIDINONE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Zhejiang Zhuji United Chemicals Co., Ltd. (CN) | 2022-03-24 | — | — | US | disclosed |
| EP-3971170-A1 | HIGH-PURITY THERMOSTABLE CRYSTAL FORM OF SUBSTITUTED 3-ISOXAZOLIDINONE COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Zhejiang Zhuji United Chemicals Co., Ltd (CN) | 2022-03-23 | — | — | EP | disclosed |
| CN-109970672-B | Crystal form of high-purity thermostable substituted 3-isoxazolidinone compound, preparation method and application | 浙江省诸暨合力化学对外贸易有限公司 | 2021-07-13 | — | — | CN | disclosed |
| CN-109776442-B | Method for preparing high-purity 3-isoxazolidinone compound crystal, crystal form and application thereof | 浙江省诸暨合力化学对外贸易有限公司 | 2021-07-06 | — | — | CN | disclosed |
| WO-2020227875-A1 | HIGH-PURITY THERMOSTABLE CRYSTAL FORM OF SUBSTITUTED 3-ISOXAZOLIDINONE COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 浙江省诸暨合力化学对外贸易有限公司 | 2020-11-19 | — | — | WO | disclosed |
| US-10626095-B2 | Cyanotriazole compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2020-04-21 | — | — | US | disclosed |
| CN-109970672-A | A kind of high-purity thermostabilization replaces the crystal form and preparation method and application of 3- isoxazole alkanone compound | 浙江省诸暨合力化学对外贸易有限公司 | 2019-07-05 | — | — | CN | disclosed |
| CN-109776442-A | A kind of method preparing high-purity 3- isoxazole alkanone compound crystal and its crystal form and application | 浙江省诸暨合力化学对外贸易有限公司 | 2019-05-21 | — | — | CN | disclosed |
| EP-3079685-A1 | SULFAMATE DERIVATIVE COMPOUNDS FOR USE IN TREATING OR ALLEVIATING PAIN | Bio-Pharm Solutions Co., Ltd. (KR) | 2016-10-19 | — | — | EP | disclosed |
| EP-0998468-A1 | SUBSTITUTED 3-PHENYL ISOXAZOLINES | BASF AKTIENGESELLSCHAFT (DE) | 2000-05-10 | — | — | EP | disclosed |
| WO-2000023413-A1 | METHOD FOR DRYING PHENOXYMETHYLBENZOIC ACIDS | BASF AKTIENGESELLSCHAFT (DE) | 2000-04-27 | — | — | WO | disclosed |
| EP-0971904-A1 | NOVEL 1-AMINO-3 BENZYL URACILS | BASF AKTIENGESELLSCHAFT (DE) | 2000-01-19 | — | — | EP | disclosed |
| WO-1999005130-A1 | SUBSTITUTED 3-PHENYL ISOXAZOLINES | BASF AKTIENGESELLSCHAFT (DE) | 1999-02-04 | — | — | WO | disclosed |
| EP-0891336-A1 | SUBSTITUTED 1-METHYL-3-BENZYLURACILS | BASF AKTIENGESELLSCHAFT (DE) | 1999-01-20 | — | — | EP | disclosed |
| WO-1998042682-A1 | NOVEL 1-AMINO-3 BENZYL URACILS | BASF AKTIENGESELLSCHAFT (DE) | 1998-10-01 | — | — | WO | disclosed |
| CN-1189824-A | 1-amino-3-benzyluracils | BASF AG (DE) | 1998-08-05 | — | — | CN | disclosed |
| EP-0835248-A1 | 1-AMINO-3-BENZYLURACILS | BASF AKTIENGESELLSCHAFT (DE) | 1998-04-15 | — | — | EP | disclosed |
| WO-1997035845-A1 | SUBSTITUTED 1-METHYL-3-BENZYLURACILS | BASF AKTIENGESELLSCHAFT (DE) | 1997-10-02 | — | — | WO | disclosed |
| WO-1997001543-A1 | 1-AMINO-3-BENZYLURACILS | BASF AKTIENGESELLSCHAFT (DE) | 1997-01-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10626095-B2 | Cyanotriazole compounds | CS, PC, ACAT1 | PAM 2761/4885SIGMAR1 4091/4885IDO1 2430/4885 |
| US-20220089553-A1 | HIGH-PURITY THERMOSTABLE CRYSTAL FORM OF SUBSTITUTED 3-ISOXAZOLIDINONE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | CYP51A1, WEE2, WEE1 | PAM 3650/4885SIGMAR1 3354/4885IDO1 3942/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.