Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1B | P35368 | 3/20 | 0.55 |
| ▸ | DRD3 | P35462 | 5/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.53 |
| ▸ | DRD2 | P14416 | 4/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.52 |
| ▸ | HTR7 | P34969 | 2/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 2/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9484247 | 0.84 | KDM4E (0.59) | ADRA1BDRD3ADRA1ADRD2ADRA1D | |
| SCHEMBL10672521 | 0.83 | DRD2 (0.47) | ADRA1BDRD3DRD2DRD4LMNA | |
| SCHEMBL917689 | 0.83 | HTR7 (0.54) | DRD3ADRA1ADRD2HTR7ALDH1A1 | |
| SCHEMBL9483949 | 0.83 | DRD2 (0.67) | ADRA1BDRD3ADRA1ADRD2ADRA1D | |
| SCHEMBL9118899 | 0.81 | DRD2 (0.54) | ADRA1BDRD3ADRA1ADRD2ADRA1D | |
| SCHEMBL917869 | 0.81 | KCNH2 (0.67) | DRD3DRD2HTR7HTR1ADRD4 | |
| SCHEMBL21009569 | 0.81 | ADRA1B (0.58) | ADRA1BDRD3ADRA1ADRD2ADRA1D | |
| SCHEMBL9484192 | 0.80 | FAAH (0.54) | ADRA1BDRD3ADRA1ADRD2ADRA1D | |
| SCHEMBL3200095 | 0.79 | ADRA1B (0.56) | ADRA1BDRD3ADRA1ADRD2ADRA1D | |
| SCHEMBL11213938 | 0.79 | MEN1 (0.62) | ADRA1BDRD3ADRA1ADRD2ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0278008-B1 | TAURINE TYPE COMPOUNDS | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1993-01-20 | — | — | EP | disclosed |
| US-4870078-A | TAURINE-TYPE COMPOUNDS | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1989-09-26 | — | — | US | disclosed |
| EP-0278008-A1 | TAURINE TYPE COMPOUNDS | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1988-08-17 | — | — | EP | disclosed |