Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.54 |
| ▸ | DRD3 | P35462 | 4/20 | 0.54 |
| ▸ | DRD2 | P14416 | 5/20 | 0.53 |
| ▸ | HTR1A | P08908 | 4/20 | 0.53 |
| ▸ | HTR2A | P28223 | 3/20 | 0.53 |
| ▸ | HTR7 | P34969 | 3/20 | 0.53 |
| ▸ | HTR6 | P50406 | 2/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL917689 | 0.83 | HTR7 (0.54) | DRD3DRD2HTR7ADRA1AGAA | |
| SCHEMBL9484247 | 0.81 | KDM4E (0.59) | DRD3DRD2HTR1AADRA1DADRA1A | |
| SCHEMBL3209304 | 0.81 | FAAH (0.55) | FAAHDRD3DRD2HTR1AHTR2A | |
| SCHEMBL10672521 | 0.80 | DRD2 (0.47) | DRD3DRD2ADRA1BDRD4 | |
| SCHEMBL9484162 | 0.80 | ADRA1B (0.55) | FAAHDRD3DRD2HTR1AHTR7 | |
| SCHEMBL2090844 | 0.80 | HTR1A (0.55) | FAAHDRD3DRD2HTR1AHTR2A | |
| SCHEMBL8828520 | 0.80 | CYP2D6 (0.56) | FAAHDRD3DRD2HTR1AHTR2A | |
| SCHEMBL3209314 | 0.79 | DRD2 (0.57) | FAAHDRD3DRD2HTR1AHTR2A | |
| SCHEMBL2091264 | 0.79 | DRD2 (0.57) | FAAHDRD3DRD2HTR1AHTR2A | |
| SCHEMBL9118899 | 0.78 | DRD2 (0.54) | DRD3DRD2HTR1AHTR7ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0278008-B1 | TAURINE TYPE COMPOUNDS | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1993-01-20 | — | — | EP | disclosed |
| US-4870078-A | TAURINE-TYPE COMPOUNDS | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1989-09-26 | — | — | US | disclosed |
| EP-0278008-A1 | TAURINE TYPE COMPOUNDS | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1988-08-17 | — | — | EP | disclosed |