Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | BID | P55957 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 3/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.41 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | EP300 | Q09472 | 2/20 | 0.41 |
| ▸ | KAT5 | Q92993 | 2/20 | 0.41 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 6/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9686955 | 0.77 | PPARA (0.41) | PPARABIDMCL1KAT8BCL2L1 | |
| SCHEMBL28104238 | 0.75 | GPR35 (0.55) | BIDMCL1BCL2L1BAK1GPR35 | |
| Benzene SCHEMBL28708360 | 0.74 | MEN1 (0.44) | PPARABIDMCL1KAT8BCL2L1 | |
| SCHEMBL5278960 | 0.70 | GABRP (0.45) | PPARABIDMCL1KAT8BCL2L1 | |
| SCHEMBL23827438 | 0.70 | MAPT (0.41) | PPARABIDMCL1KAT8BCL2L1 | |
| SCHEMBL27370565 | 0.70 | CA2 (0.42) | GPR35ALDH1A1 | |
| Water SCHEMBL11492577 | 0.69 | MAPT (0.40) | PPARABIDMCL1KAT8BCL2L1 | |
| SCHEMBL9724742 | 0.69 | KDM4E (0.42) | GPR35CNR2ALDH1A1 | |
| SCHEMBL6065355 | 0.68 | GPR35 (0.43) | PPARABIDMCL1KAT8BCL2L1 | |
| SCHEMBL3260662 | 0.68 | BID (0.68) | PPARABIDMCL1KAT8BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5202328-A | Treatment of hypertension, congestive heart failure, glaucoma | MERCK & CO., INC. (US) | 1993-04-13 | — | — | US | disclosed |