Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | MPI | P34949 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5608458 | 0.83 | TSHR (0.43) | KMT2AACHETSHRLMNACYP2C9 | |
| SCHEMBL3278966 | 0.82 | ACHE (0.50) | KMT2AACHETSHRLMNACYP2C9 | |
| SCHEMBL9487839 | 0.82 | ALDH1A1 (0.38) | KMT2AACHELMNAHTTALDH1A1 | |
| SCHEMBL9487832 | 0.77 | TSHR (0.50) | KMT2AACHETSHRLMNACYP2C9 | |
| SCHEMBL1921836 | 0.77 | HSP90AA1 (0.40) | ACHETSHRHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL9486403 | 0.76 | MAPT (0.43) | KMT2AACHETSHRALDH1A1MAPT | |
| SCHEMBL9487992 | 0.75 | KMT2A (0.42) | KMT2AACHETSHRLMNACYP2C9 | |
| SCHEMBL8378007 | 0.73 | TP53 (0.45) | KMT2AACHETSHRLMNACYP2C9 | |
| SCHEMBL9488797 | 0.73 | TDP2 (0.34) | TSHRSMN1; SMN2CYP1A2 | |
| SCHEMBL5608705 | 0.72 | TSHR (0.50) | KMT2AACHETSHRSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250657-A | Process for preparing polyarylene thioether | SEISAN KAIHATSU KAGAKU KENKYUSHO (JP) | 1993-10-05 | — | — | US | disclosed |
| EP-0440106-A2 | Process for preparing polyarylene thioethers | SEISAN KAIHATSU KAGAKU KENKYUSHO (JP) | 1991-08-07 | — | — | EP | disclosed |