Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 7/20 | 0.51 |
| ▸ | DPP4 | P27487 | 6/20 | 0.51 |
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.51 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.47 |
| ▸ | FAP | Q12884 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | Q9HBH1 | 1/20 | 0.41 | |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11453560 | 0.87 | DPP4 (0.47) | DPP8DPP4DPP7DPP9FAP | |
| SCHEMBL30608510 | 0.87 | DPP4 (0.50) | DPP8DPP4DPP7DPP9LMNA | |
| SCHEMBL6417819 | 0.86 | LMNA (0.46) | DPP8DPP4DPP7DPP9LMNA | |
| SCHEMBL9011317 | 0.83 | DPP4 (0.58) | DPP8DPP4DPP7DPP9FAP | |
| SCHEMBL1257864 | 0.83 | LMNA (0.53) | DPP8DPP4DPP7DPP9LMNA | |
| SCHEMBL9490722 | 0.81 | DPP8 (0.54) | DPP8DPP4DPP7DPP9FAP | |
| SCHEMBL31139625 | 0.81 | DPP8 (0.42) | DPP8DPP4DPP7DPP9LMNA | |
| SCHEMBL873647 | 0.80 | DPP8 (0.49) | DPP8DPP4DPP7DPP9FAP | |
| SCHEMBL4372297 | 0.80 | NAMPT (0.53) | LMNANAMPTMMP2MMP9ALDH1A1 | |
| SCHEMBL18509855 | 0.80 | NAMPT (0.53) | LMNANAMPTMMP2MMP9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255341-B1 | REAGENT FOR TESTING PERIODONTAL DISEASES | SUNSTAR KABUSHIKI KAISHA (JP) | 1993-02-03 | — | — | EP | disclosed |
| US-5137811-A | Method for diagnosing periodontal diseases with a substrate specific for aminopeptidase activity of periodontopathic bacteria | SUNSTAR KABUSHIKI KAISHA (JP) | 1992-08-11 | — | — | US | disclosed |