Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 6/20 | 0.47 |
| ▸ | EDNRA | P25101 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GALK1 | P51570 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL916737 | 0.80 | ALDH1A1 (0.53) | EDNRBEDNRAALDH1A1MEN1KMT2A | |
| SCHEMBL28850201 | 0.80 | ALDH1A1 (0.53) | EDNRBEDNRAALDH1A1MEN1KMT2A | |
| SCHEMBL2452597 | 0.78 | KDM4E (0.55) | EDNRBEDNRAALDH1A1NPC1MEN1 | |
| SCHEMBL5156270 | 0.78 | MAOB (0.43) | ALDH1A1MAOB | |
| SCHEMBL5158375 | 0.74 | LMNA (0.55) | ALDH1A1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL32690147 | 0.70 | ALDH1A1 (0.40) | EDNRBEDNRAALDH1A1MEN1KMT2A | |
| SCHEMBL28322348 | 0.69 | MAPT (0.44) | EDNRBEDNRANPC1MEN1MAPT | |
| Hydrochloric Acid SCHEMBL8565575 | 0.69 | ALDH1A1 (0.35) | ALDH1A1KDM4E | |
| SCHEMBL7503965 | 0.69 | MEN1 (0.44) | EDNRBEDNRAALDH1A1NPC1MEN1 | |
| SCHEMBL18387977 | 0.69 | SIGMAR1 (0.41) | EDNRBEDNRAMAOBFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496836-A4 | SYNTHESIS AND USE OF AMINO ACID FLUORIDES AS PEPTIDE COUPLING REAGENTS | — | 1993-05-05 | — | — | EP | disclosed |
| EP-0496836-A1 | SYNTHESIS AND USE OF AMINO ACID FLUORIDES AS PEPTIDE COUPLING REAGENTS. | RES CORP TECHNOLOGIES INC (US) | 1992-08-05 | — | — | EP | disclosed |