Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSG | P08311 | 1/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10461110 | 0.86 | NPSR1 (0.51) | ALDH1A1MEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL9490572 | 0.83 | MMP2 (0.55) | ALDH1A1MEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL9490445 | 0.83 | MMP2 (0.54) | CTSGCMA1ALDH1A1MEN1KMT2A | |
| SCHEMBL9490432 | 0.78 | MMP2 (0.54) | CTSGCMA1ALDH1A1MEN1KMT2A | |
| SCHEMBL9490689 | 0.78 | MMP2 (0.54) | CTSGCMA1ALDH1A1MEN1KMT2A | |
| SCHEMBL9489398 | 0.78 | MMP2 (0.56) | CTSGCMA1ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL9490990 | 0.74 | NPSR1 (0.53) | ALDH1A1MEN1KMT2AHTTSMN1; SMN2 | |
| Acetic Acid SCHEMBL10461101 | 0.71 | MMP2 (0.53) | ALDH1A1MEN1KMT2AHSD17B10MAPT | |
| SCHEMBL8814333 | 0.70 | KMT2A (0.46) | CTSGCMA1ALDH1A1MEN1KMT2A | |
| SCHEMBL9491040 | 0.70 | MAPT (0.53) | ALDH1A1MEN1KMT2AHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266102-B1 | QUINOXALINONE DERIVATIVES | PFIZER INC. (US) | 1993-03-17 | — | — | EP | disclosed |
| US-4940708-A | 4-arylsulfonyl-3,4-dihydro-2(1H)-quinoxalinone-1-alkanoic acids, esters, and salts | PFIZER INC. (US) | 1990-07-10 | — | — | US | disclosed |