Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.49 |
| ▸ | CTSG | P08311 | 1/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9490572 | 0.91 | MMP2 (0.55) | MMP2ALDH1A1MEN1KMT2APKM | |
| SCHEMBL9490689 | 0.88 | MMP2 (0.54) | MMP2ALDH1A1MEN1KMT2ACTSG | |
| SCHEMBL9490445 | 0.88 | MMP2 (0.54) | MMP2ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL9489398 | 0.85 | MMP2 (0.56) | MMP2ALDH1A1CTSGCMA1PKM | |
| SCHEMBL9699725 | 0.84 | NPSR1 (0.49) | MMP2ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL9490595 | 0.78 | CTSG (0.44) | MMP2ALDH1A1MEN1KMT2ACTSG | |
| SCHEMBL9490990 | 0.76 | NPSR1 (0.53) | MMP2ALDH1A1MEN1KMT2AGAA | |
| Acetic Acid SCHEMBL10461101 | 0.76 | MMP2 (0.53) | MMP2ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL10459002 | 0.74 | L3MBTL1 (0.50) | ALDH1A1MEN1KMT2AGAAPKM | |
| SCHEMBL9697221 | 0.74 | KMT2A (0.53) | MMP2ALDH1A1MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266102-B1 | QUINOXALINONE DERIVATIVES | PFIZER INC. (US) | 1993-03-17 | — | — | EP | disclosed |
| US-4940708-A | 4-arylsulfonyl-3,4-dihydro-2(1H)-quinoxalinone-1-alkanoic acids, esters, and salts | PFIZER INC. (US) | 1990-07-10 | — | — | US | disclosed |