Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | APLNR | P35414 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9494117 | 0.86 | KDM4E (0.38) | LMNAAPLNRMAPTKDM4ERAB9A | |
| SCHEMBL9492707 | 0.81 | APLNR (0.34) | APLNRMAPTKDM4EHTTRAB9A | |
| SCHEMBL9491571 | 0.79 | KDM4E (0.37) | LMNAAPLNRMAPTKDM4ERAB9A | |
| SCHEMBL8357511 | 0.76 | ALOX15 (0.35) | LMNA | |
| SCHEMBL789857 | 0.76 | ABCB11 (0.36) | CMKLR1 | |
| SCHEMBL9637462 | 0.70 | BRS3 (0.37) | APLNRMAPTKDM4EHTT | |
| SCHEMBL8359387 | 0.70 | TSHR (0.38) | LMNAMAPTKDM4EHTTRAB9A | |
| SCHEMBL9493716 | 0.69 | BRS3 (0.39) | — | |
| SCHEMBL8357507 | 0.69 | FGFR1 (0.34) | LMNA | |
| SCHEMBL8868610 | 0.68 | PARP1 (0.36) | LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5243054-A | Hypotensive agents, cardiovascular disorders or nervous system disorders | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-09-07 | — | — | US | disclosed |