Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPD1 | P10809 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Zinc Ion SCHEMBL9496396 | 0.97 | HSPD1 (0.51) | HSPD1BLMHSPE1CA2MEN1 | |
| SCHEMBL31158245 | 0.97 | HSPD1 (0.51) | HSPD1BLMHSPE1CA2MEN1 | |
| Potassium Ion SCHEMBL31158247 | 0.97 | HSPD1 (0.51) | HSPD1BLMHSPE1CA2MEN1 | |
| Tetramethylammonium Ion SCHEMBL31158235 | 0.94 | HSPD1 (0.49) | HSPD1BLMHSPE1CA2MEN1 | |
| Tetrabuthylammonium SCHEMBL31158248 | 0.91 | HSPD1 (0.47) | HSPD1BLMHSPE1CA2MEN1 | |
| SCHEMBL9516374 | 0.88 | HSPD1 (0.63) | HSPD1BLMHSPE1CA2MEN1 | |
| SCHEMBL9513919 | 0.88 | HSPD1 (0.63) | HSPD1BLMHSPE1CA2MEN1 | |
| SCHEMBL9724548 | 0.88 | HSPD1 (0.63) | HSPD1BLMHSPE1CA2MEN1 | |
| SCHEMBL9513929 | 0.86 | HSPD1 (0.66) | HSPD1BLMHSPE1CA2MEN1 | |
| SCHEMBL9516386 | 0.86 | HSPD1 (0.66) | HSPD1BLMHSPE1CA2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0527165-A1 | USE OF METAL SOAPS OF POLYCARBOXYLIC ACIDS OR POLYCARBOXYLIC ACID PARTIAL ESTERS AS PROCESSING AIDS FOR POLYESTERS | Henkel Kommanditgesellschaft auf Aktien (DE) | 1993-02-17 | — | — | EP | disclosed |
| WO-1991017208-A1 | USE OF METAL SOAPS OF POLYCARBOXYLIC ACIDS OR POLYCARBOXYLIC ACID PARTIAL ESTERS AS PROCESSING AIDS FOR POLYESTERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1991-11-14 | — | — | WO | disclosed |