Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10144468 | 0.84 | LMNA (0.40) | HTTLMNAALDH1A1KDM4EPOLB | |
| SCHEMBL1314802 | 0.79 | HTT (0.43) | HTTSMN1; SMN2LMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL502252 | 0.77 | HTT (0.42) | HTTSMN1; SMN2LMNAALDH1A1KDM4E | |
| SCHEMBL10456934 | 0.77 | NOS3 (0.39) | HTTLMNAALDH1A1KDM4EMEN1 | |
| SCHEMBL3124697 | 0.74 | ALDH1A1 (0.36) | HTTLMNAALDH1A1KDM4EMEN1 | |
| SCHEMBL11859138 | 0.74 | PGK1 (0.39) | HTTLMNAALDH1A1KDM4EMEN1 | |
| SCHEMBL10728370 | 0.73 | MAPK1 (0.54) | HTTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL13008173 | 0.73 | LMNA (0.40) | HTTLMNAKDM4EMEN1KMT2A | |
| SCHEMBL8194463 | 0.71 | ALDH1A1 (0.50) | HTTALDH1A1KDM4ENOS3NOS1 | |
| SCHEMBL5821732 | 0.71 | PTGS2 (0.54) | HTTLMNAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264437-A | Antiinflammatory agents, immunosuppressants or antiallergens | SYNTEX (U.S.A.) INC. (US) | 1993-11-23 | — | — | US | disclosed |