Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBS | P35520 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9494438 | 0.88 | EPHX1 (0.40) | EPHX1EPHX2MEN1KMT2ANPC1 | |
| SCHEMBL9494589 | 0.83 | NPC1 (0.45) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL9495344 | 0.80 | TP53 (0.33) | EPHX1EPHX2TSHRMEN1KMT2A | |
| SCHEMBL9496601 | 0.75 | TSHR (0.49) | TSHRMEN1KMT2ANPC1RAB9A | |
| SCHEMBL9495354 | 0.74 | HTT (0.44) | TSHRMEN1KMT2AMAPTLMNA | |
| SCHEMBL9497253 | 0.74 | MAPT (0.46) | TSHRMEN1KMT2ANPC1RAB9A | |
| SCHEMBL9499116 | 0.73 | MAPT (0.32) | MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL5254243 | 0.69 | MAPT (0.33) | EPHX1EPHX2TSHRNPC1RAB9A | |
| SCHEMBL9498592 | 0.68 | NPC1 (0.41) | CBSEPHX1EPHX2TSHRMEN1 | |
| SCHEMBL5010680 | 0.67 | TSHR (0.33) | TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264437-A | Antiinflammatory agents, immunosuppressants or antiallergens | SYNTEX (U.S.A.) INC. (US) | 1993-11-23 | — | — | US | disclosed |