Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5254243 | 0.88 | MAPT (0.33) | TP53SMN1; SMN2TSHREPHX1EPHX2 | |
| SCHEMBL9495288 | 0.84 | NPC1 (0.40) | SMN1; SMN2TSHRMEN1KMT2ANPC1 | |
| SCHEMBL9494589 | 0.84 | NPC1 (0.45) | SMN1; SMN2MEN1KMT2ACYP1A2NPC1 | |
| SCHEMBL9495354 | 0.81 | HTT (0.44) | SMN1; SMN2TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL9497253 | 0.81 | MAPT (0.46) | TP53SMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL9498587 | 0.80 | CBS (0.41) | SMN1; SMN2TSHRMEN1KMT2AEPHX1 | |
| SCHEMBL9499116 | 0.77 | MAPT (0.32) | TP53SMN1; SMN2MEN1KMT2AHSD17B10 | |
| SCHEMBL9496601 | 0.74 | TSHR (0.49) | SMN1; SMN2TSHRMEN1KMT2ANPC1 | |
| SCHEMBL5010680 | 0.73 | TSHR (0.33) | TSHRKMT2ATDP1HSD17B10MAPK1 | |
| SCHEMBL9499230 | 0.72 | TSHR (0.39) | SMN1; SMN2TSHRMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264437-A | Antiinflammatory agents, immunosuppressants or antiallergens | SYNTEX (U.S.A.) INC. (US) | 1993-11-23 | — | — | US | disclosed |