Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | CLK3 | P49761 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL953933 | 0.88 | CYP3A4 (0.40) | HPGDTSHRKDM4ECYP1A2ALDH1A1 | |
| SCHEMBL956335 | 0.82 | HPGD (0.60) | SMN1; SMN2HPGDUSP2TSHRNPSR1 | |
| SCHEMBL954665 | 0.78 | KDM4E (0.41) | KDM4EALDH1A1GSK3AMAPTLMNA | |
| SCHEMBL20777974 | 0.77 | RAB9A (0.51) | SMN1; SMN2HPGDKDM4EALDH1A1MAPT | |
| SCHEMBL28569542 | 0.77 | RAB9A (0.51) | SMN1; SMN2HPGDKDM4EALDH1A1MAPT | |
| SCHEMBL26318663 | 0.73 | SOAT2 (0.58) | SMN1; SMN2HPGDUSP2TSHRNPSR1 | |
| SCHEMBL20777937 | 0.73 | PSMB11 (0.60) | HPGDNPSR1CYP1A2ALDH1A1CYP2C9 | |
| SCHEMBL20777929 | 0.72 | PSMB11 (0.62) | SMN1; SMN2HPGDNPSR1CYP1A2ALDH1A1 | |
| SCHEMBL20777938 | 0.71 | ALDH1A1 (0.48) | HPGDNPSR1CYP1A2ALDH1A1ALOX12 | |
| SCHEMBL11304280 | 0.70 | ALDH1A1 (0.62) | SMN1; SMN2HPGDKDM4ECYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011006935-A2 | TETRAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2011-01-20 | — | — | WO | disclosed |