Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26318663 | 0.90 | SOAT2 (0.58) | HPGDSMN1; SMN2USP2TSHRNPSR1 | |
| SCHEMBL950001 | 0.88 | CYP3A4 (0.60) | HPGDSMN1; SMN2USP2KDM4EMAPT | |
| SCHEMBL949484 | 0.82 | SMN1; SMN2 (0.42) | HPGDSMN1; SMN2USP2TSHRNPSR1 | |
| Tazanolast SCHEMBL28495 | 0.82 | HPGD (0.45) | HPGDSMN1; SMN2USP2TSHRNPSR1 | |
| SCHEMBL6694019 | 0.81 | MAPT (0.59) | HPGDSMN1; SMN2TSHRKDM4EMAPT | |
| SCHEMBL22167182 | 0.81 | MGLL (0.54) | MAPTLMNAHTTALDH1A1MEN1 | |
| SCHEMBL28569542 | 0.81 | RAB9A (0.51) | HPGDSMN1; SMN2KDM4EMAPTLMNA | |
| SCHEMBL20777974 | 0.81 | RAB9A (0.51) | HPGDSMN1; SMN2KDM4EMAPTLMNA | |
| SCHEMBL9314587 | 0.79 | MGLL (0.45) | HPGDSMN1; SMN2TSHRKDM4EMAPT | |
| SCHEMBL954665 | 0.79 | KDM4E (0.41) | KDM4EMAPTLMNAALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011006935-A2 | TETRAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2011-01-20 | — | — | WO | disclosed |