Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.39 |
| ▸ | RORC | P51449 | 2/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20777935 | 0.84 | SOAT1 (0.46) | ALDH1A1SOAT1TP53MAPT | |
| SCHEMBL20777938 | 0.82 | ALDH1A1 (0.48) | ALDH1A1SOAT1TP53MAPT | |
| SCHEMBL956335 | 0.79 | HPGD (0.60) | KDM4EALDH1A1GSK3ALMNATP53 | |
| SCHEMBL20777974 | 0.79 | RAB9A (0.51) | KDM4EALDH1A1SOAT1POLBLMNA | |
| SCHEMBL28569542 | 0.79 | RAB9A (0.51) | KDM4EALDH1A1SOAT1POLBLMNA | |
| SCHEMBL949484 | 0.78 | SMN1; SMN2 (0.42) | KDM4EALDH1A1GSK3ARORCADORA1 | |
| SCHEMBL1309175 | 0.77 | ALDH1A1 (0.58) | KDM4EALDH1A1POLB | |
| SCHEMBL20777929 | 0.73 | PSMB11 (0.62) | ALDH1A1SOAT1POLBLMNATP53 | |
| SCHEMBL26318663 | 0.72 | SOAT2 (0.58) | KDM4EALDH1A1SOAT1POLBLMNA | |
| SCHEMBL23412427 | 0.72 | KDM4E (0.50) | KDM4EALDH1A1SOAT1CETPPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011006935-A2 | TETRAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2011-01-20 | — | — | WO | disclosed |