Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.40 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9499230 | 0.88 | TSHR (0.39) | NPC1RAB9AHPGDMEN1KMT2A | |
| SCHEMBL9495344 | 0.84 | TP53 (0.33) | NPC1RAB9AHPGDMEN1KMT2A | |
| SCHEMBL9494589 | 0.84 | NPC1 (0.45) | NPC1RAB9AMEN1KMT2AHTT | |
| SCHEMBL9494500 | 0.82 | KMT2A (0.46) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL9495354 | 0.81 | HTT (0.44) | MEN1KMT2AHTTALDH1A1TSHR | |
| SCHEMBL9497253 | 0.81 | MAPT (0.46) | NPC1RAB9AHPGDMEN1KMT2A | |
| SCHEMBL9498587 | 0.77 | CBS (0.41) | NPC1RAB9AMEN1KMT2AHTT | |
| SCHEMBL27804210 | 0.74 | NOTUM (0.42) | HPGDMEN1KMT2AALDH1A1POLB | |
| SCHEMBL5254243 | 0.73 | MAPT (0.33) | NPC1RAB9AALDH1A1POLBTDP1 | |
| SCHEMBL9499116 | 0.72 | MAPT (0.32) | MEN1KMT2APOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264437-A | Antiinflammatory agents, immunosuppressants or antiallergens | SYNTEX (U.S.A.) INC. (US) | 1993-11-23 | — | — | US | disclosed |