Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ENPP3 | O14638 | 5/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 4/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9494430 | 0.87 | YAP1 (0.40) | TRPM8CA1CA2CA9 | |
| SCHEMBL9494256 | 0.86 | PPARG (0.38) | TRPM8ENPP1 | |
| SCHEMBL9495195 | 0.86 | KMT2A (0.40) | TRPM8ALDH1A1 | |
| SCHEMBL9492475 | 0.85 | MGLL (0.42) | TRPM8POLBALDH1A1 | |
| SCHEMBL9491411 | 0.83 | ALDH1A1 (0.35) | POLBMAOBALDH1A1 | |
| SCHEMBL9492135 | 0.80 | DPP4 (0.35) | — | |
| SCHEMBL9504915 | 0.78 | CCNC (0.40) | TRPM8ALDH1A1 | |
| SCHEMBL9492617 | 0.78 | KMT2A (0.40) | TRPM8 | |
| SCHEMBL9493429 | 0.76 | DPP4 (0.38) | POLBALDH1A1 | |
| SCHEMBL9377407 | 0.75 | CNR1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5211739-A | Herbicidal-1-(disubstituted carbamoyl or thiocarbamoyl)-1,2,4-triazol-3-yl sulfonates and thisulfonates | ROHM AND HAAS COMPANY (US) | 1993-05-18 | — | — | US | claimed |