Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | BRPF1 | P55201 | 5/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | F11 | P03951 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | BRD1 | O95696 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31202712 | 0.81 | BRPF1 (0.62) | BRPF1RXFP1CA12CA9BRD1 | |
| SCHEMBL9494686 | 0.77 | RXFP1 (0.50) | DAOBRPF1HTR2AHTR2CCYP2A6 | |
| SCHEMBL17610037 | 0.75 | CA12 (0.39) | BRPF1HTR2AHTR2CRXFP1OXER1 | |
| SCHEMBL9499012 | 0.73 | KDM4E (0.50) | HTR2CCYP2A6KDM4ELMNAL3MBTL1 | |
| SCHEMBL9498050 | 0.73 | LDHA (0.59) | DAO | |
| SCHEMBL30042221 | 0.73 | KMO (0.39) | HTR2AHTR2CF11CYP2A6OXER1 | |
| SCHEMBL347208 | 0.72 | MAPT (0.45) | OXER1KMOCCR2 | |
| SCHEMBL271495 | 0.71 | CA12 (0.63) | DAOBRPF1CA12CA9KDM4E | |
| SCHEMBL2795278 | 0.70 | PTGER4 (0.37) | HTR2AHTR2CF11OXER1KMO | |
| SCHEMBL2796941 | 0.70 | MAPT (0.39) | OXER1KMOHTTCCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240859-B1 | LIPOXYGENASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1993-04-28 | — | — | EP | disclosed |
| US-4761403-A | QUINOLONE DERIVATIVES | ABBOTT LABORATORIES (US) | 1988-08-02 | — | — | US | disclosed |
| EP-0240859-A2 | Lipoxygenase inhibiting compounds | ABBOTT LABORATORIES (US) | 1987-10-14 | — | — | EP | disclosed |