Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | PPIA | P62937 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5252939 | 0.90 | RAB9A (0.45) | TSHRMAPTKMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL9499264 | 0.77 | TSHR (0.35) | TSHRMAPTKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL9498587 | 0.75 | CBS (0.41) | TSHRMAPTKMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL9495344 | 0.74 | TP53 (0.33) | TSHRMAPTKMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL9496610 | 0.74 | MAPT (0.47) | TSHRMAPTKMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL2312502 | 0.71 | KMT2A (0.75) | TSHRMAPTKMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL2312499 | 0.71 | KMT2A (0.75) | TSHRMAPTKMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL10600161 | 0.69 | MEN1 (0.43) | TSHRKMT2ARAB9ANPC1MEN1 | |
| SCHEMBL9494997 | 0.69 | — | — | |
| SCHEMBL9495354 | 0.69 | HTT (0.44) | TSHRMAPTKMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264437-A | Antiinflammatory agents, immunosuppressants or antiallergens | SYNTEX (U.S.A.) INC. (US) | 1993-11-23 | — | — | US | disclosed |