Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9493946 | 0.90 | LMNA (0.34) | MEN1KMT2APOLBALDH1A1TDP1 | |
| SCHEMBL9494997 | 0.81 | — | — | |
| SCHEMBL10600161 | 0.79 | MEN1 (0.43) | TSHRMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL9495202 | 0.79 | ALOX15 (0.30) | — | |
| SCHEMBL9496601 | 0.77 | TSHR (0.49) | TSHRMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL9499268 | 0.74 | POLB (0.32) | TSHRMEN1KMT2APOLBHCAR3 | |
| SCHEMBL9497849 | 0.71 | — | — | |
| SCHEMBL9495344 | 0.69 | TP53 (0.33) | TSHRMEN1KMT2APOLBHCAR3 | |
| SCHEMBL9493952 | 0.68 | ALDH1A1 (0.33) | POLBALDH1A1TDP1LMNASMN1; SMN2 | |
| SCHEMBL10969677 | 0.67 | KMT2A (0.47) | TSHRMEN1KMT2APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264437-A | Antiinflammatory agents, immunosuppressants or antiallergens | SYNTEX (U.S.A.) INC. (US) | 1993-11-23 | — | — | US | disclosed |