Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.41 |
| ▸ | SYK | P43405 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19914820 | 0.81 | MAPT (0.60) | ALDH1A1CYP1A2CYP3A4KMT2AMEN1 | |
| SCHEMBL5974410 | 0.78 | PKM (0.46) | ALDH1A1KMT2AMEN1HSD17B10MAPT | |
| SCHEMBL7723797 | 0.78 | CYP3A4 (0.54) | ALDH1A1CYP1A2CYP3A4TSHRRAPGEF4 | |
| SCHEMBL11385963 | 0.77 | RAB9A (0.58) | ALDH1A1CYP1A2TSHRKMT2AMEN1 | |
| SCHEMBL20897137 | 0.76 | ALDH1A1 (0.46) | ALDH1A1CYP1A2CYP3A4TSHRKMT2A | |
| SCHEMBL55730 | 0.76 | CYP3A4 (0.52) | ALDH1A1CYP1A2CYP3A4TSHRRAPGEF4 | |
| SCHEMBL2364427 | 0.76 | NLRP3 (0.41) | ALDH1A1NLRP3CA12CA2CA9 | |
| SCHEMBL6907026 | 0.76 | ALDH1A1 (0.57) | ALDH1A1CYP1A2KMT2ANLRP3SYK | |
| SCHEMBL11508113 | 0.76 | CYP3A4 (0.56) | ALDH1A1CYP1A2CYP3A4TSHRRAPGEF4 | |
| Hydrochloric Acid SCHEMBL11309314 | 0.76 | CYP3A4 (0.52) | ALDH1A1CYP1A2CYP3A4TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5132460-A | — | — | None | — | — | JP | disclosed |
| JP-H05132460-A | INDOLINE HYDROCHLORIDE AND ITS PRODUCTION | SANDOZ AG | 1993-05-28 | — | — | JP | disclosed |
| EP-0511168-A1 | Indoline hydrochloride salts and process for their preparation | SANDOZ LTD. (CH) | 1992-10-28 | — | — | EP | disclosed |