Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | LPL | P06858 | 2/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | MGLL | Q99685 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3785277 | 0.78 | LPL (0.46) | NLRP3LPLLIPGENPP2KDM4E | |
| SCHEMBL22023200 | 0.77 | NLRP3 (0.46) | NLRP3ENPP2KDM4EALDH1A1CA12 | |
| SCHEMBL9497585 | 0.76 | ALDH1A1 (0.50) | NLRP3ALDH1A1CA12CA2CA9 | |
| SCHEMBL19914820 | 0.76 | MAPT (0.60) | KDM4EALDH1A1 | |
| SCHEMBL7820158 | 0.75 | NLRP3 (0.45) | NLRP3ENPP2KDM4EALDH1A1CA12 | |
| SCHEMBL15150688 | 0.74 | ENPP2 (0.46) | NLRP3LPLLIPGENPP2KDM4E | |
| SCHEMBL31482482 | 0.73 | ENPP2 (0.42) | NLRP3LPLLIPGENPP2KDM4E | |
| SCHEMBL5974410 | 0.73 | PKM (0.46) | KDM4EALDH1A1 | |
| SCHEMBL3191409 | 0.73 | ENPP2 (0.48) | NLRP3LPLLIPGENPP2KDM4E | |
| SCHEMBL11385963 | 0.72 | RAB9A (0.58) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7988685-B2 | Hydrogel compositions, devices, and microscale components | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2011-08-02 | — | — | US | disclosed |
| US-20040248326-A1 | Hydrogel compositions, devices, and microscale components | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2004-12-09 | — | — | US | disclosed |
| WO-2003051286-A2 | HYDROGEL COMPOSITIONS, DEVICES, AND MICROSCALE COMPONENTS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2003-06-26 | — | — | WO | disclosed |