SCHEMBL94983

SCHEMBL94983

COc1ccc(NC(C)O)cc1N

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.47
CYP3A4 P08684 1/20 0.47
LMNA P02545 1/20 0.46
HTT P42858 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
MEN1 O00255 1/20 0.46
MAPT P10636 1/20 0.46
THRB P10828 1/20 0.46
KMT2A Q03164 1/20 0.46
KDM4E B2RXH2 1/20 0.46
NPC1 O15118 1/20 0.46
ESR1 P03372 1/20 0.46
TP53 P04637 1/20 0.46
RAB9A P51151 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
ESR2 Q92731 1/20 0.46
GAA P10253 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
MMP1 P03956 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL672455 0.92 CA1 (0.49) ALDH1A1CYP3A4LMNAHTTL3MBTL1
SCHEMBL7130834 0.86 KDM4E (0.38) ALDH1A1CYP3A4LMNAHTTL3MBTL1
SCHEMBL8665713 0.83 ALDH1A1 (0.47) ALDH1A1CYP3A4LMNAHTTL3MBTL1
SCHEMBL4233801 0.81 ALDH1A1 (0.42) ALDH1A1CYP3A4LMNAHTTL3MBTL1
Hydrochloric Acid SCHEMBL8665038 0.81 ALDH1A1 (0.45) ALDH1A1CYP3A4LMNAHTTL3MBTL1
SCHEMBL16966255 0.78 ALDH1A1 (0.53) ALDH1A1CYP3A4LMNAHTTL3MBTL1
SCHEMBL11443273 0.77 TDP1 (0.43) ALDH1A1CYP3A4MEN1MAPTTHRB
SCHEMBL6229914 0.77 ALDH1A1 (0.50) ALDH1A1LMNAHTTMEN1MAPT
SCHEMBL11264661 0.76 GAA (0.57) ALDH1A1CYP3A4LMNAHTTL3MBTL1
SCHEMBL8616784 0.73 ALDH1A1 (0.56) ALDH1A1CYP3A4LMNAHTTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1606 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144724-A1 Mixture of at least five surfactants (I1) to (I5) WELLA GERMANY GMBH (DE) 2026-05-28 US claimed
US-12636241-B1 Method and composition for oxidative hair coloring WELLA OPERATIONS US LLC (US) 2026-05-26 US claimed
EP-4362892-B1 COMPOSITION COMPRISING AT LEAST ONE ALKYL (POLY)GLYCOSIDE, AT LEAST ONE FATTY ALCOHOL, AT LEAST ONE FATTY ACID, AND AT LEAST ONE ALKALINE AGENT OREAL (FR) 2026-04-15 EP claimed
US-12589063-B2 Composition comprising a combination of two particular oxidation dye precursors, an amphoteric or zwitterionic surfactant and a solid fatty substance L'OREAL (FR) 2026-03-31 US claimed
US-12564545-B2 Hair coloring compositions comprising 2-amino-1-propanol as alkalising agents WELLA GERMANY GMBH (DE) 2026-03-03 US claimed
EP-4452203-B1 PROCESS FOR DYEING KERATIN FIBRES USING A COSMETIC COMPOSITION COMPRISING PROPANE-1,3-DIOL AND A DYEING COMPOSITION OREAL (FR) 2025-12-24 EP claimed
WO-2025242864-A1 DISCOLORING COMPOSITION FOR KERATIN FIBERS DYED WITH BLEACH-STABLE DIRECT DYES KAO CORPORATION (JP) 2025-11-27 WO claimed
US-12472136-B2 Composition comprising at least one alkyl (poly)glycoside, at least one fatty alcohol, at least one fatty acid, and at least one alkaline agent L'OREAL (FR) 2025-11-18 US claimed
EP-4408377-B1 COMPOSITION COMPRISING OXIDATIVE AND DIRECT DYES KAO CORP (JP) 2025-10-08 EP claimed
US-12383482-B2 Hair coloring compositions WELLA GERMANY GMBH (DE) 2025-08-12 US claimed
EP-0835093-A1 HAIR DYE AGENTS WITH AT LEAST ONE CONDITIONER Hans Schwarzkopf GmbH & Co. KG (DE) 1998-04-15 EP claimed
EP-0589952-B1 USE OF SUPLHUR METAAMINOPHENOLS FOR DYEING KERATINIC FIBRES, TINCTORIAL COMPOSITIONS AND NOVEL COMPOUNDS OREAL (FR) 1997-08-27 EP claimed
EP-0605320-B1 Dye composition for keratinic fibres based on paraphenylenediamine, metaphenylenediamines and benzimidazol derivates, and the dyeing process using same OREAL (FR) 1997-04-09 EP claimed
WO-1997001323-A1 HAIR DYE AGENTS WITH AT LEAST ONE CONDITIONER HANS SCHWARZKOPF GMBH (DE) 1997-01-16 WO claimed
EP-0591373-B1 META-AMINOPHENOLS, THEIR USE AS COUPLERS FOR OXIDATION DYEING OF KERATINOUS FIBRES, DYE COMPOSITIONS AND METHOD OREAL (FR) 1996-05-22 EP claimed
US-5478359-A Applying a hair dyes L'OREAL (FR) 1995-12-26 US claimed
EP-0506549-B1 Dyeing composition for keratinous fibers containing oxidation dye precursors and hydroxybenzofurans as couplers and dyeing process making use of such a composition OREAL (FR) 1995-10-18 EP claimed
US-5443596-A Keratinous fiber dyeing compositions and processes utilizing oxidation dye precursors in combination with dimethoxy meta-aminophenol couplers L'OREAL (FR) 1995-08-22 US claimed
EP-0465339-B1 Keratinous fibres dyeing process with derivatives of 4-hydroxyindol at acidic pH and compositions OREAL (FR) 1993-12-29 EP claimed
US-5203875-A Hair dyes also using ortho- and para-phenylenediamines or aminophenols; colorfastness; washfastness; perspiration resistance L'OREAL (FR) 1993-04-20 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12589063-B2 Composition comprising a combination of two particular oxidation dye precursors, an amphoteric or zwitterionic surfactant and a solid fatty substance S100P, KRT18, S100A4 ALDH1A1 118/4885CYP3A4 1450/4885LMNA 759/4885
US-12564545-B2 Hair coloring compositions comprising 2-amino-1-propanol as alkalising agents PHOSPHO1, ALDH7A1, AASDHPPT ALDH1A1 173/4885CYP3A4 2567/4885LMNA 1222/4885
US-12636241-B1 Method and composition for oxidative hair coloring POLB, DAO, ALPP ALDH1A1 200/4885CYP3A4 2719/4885LMNA 1280/4885
US-20260144724-A1 Mixture of at least five surfactants (I1) to (I5) DEGS1, SGMS1, FABP4 ALDH1A1 3076/4885CYP3A4 3722/4885LMNA 3521/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.