Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9498568 | 0.87 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2LMNAUTS2RKMT2A | |
| SCHEMBL9500403 | 0.87 | UTS2R (0.53) | ALDH1A1LMNATDP1UTS2RKMT2A | |
| SCHEMBL9499271 | 0.85 | NPSR1 (0.53) | ALDH1A1LMNATDP1UTS2RKMT2A | |
| SCHEMBL9500265 | 0.82 | FAAH (0.55) | KMT2AMAPT | |
| SCHEMBL22416005 | 0.81 | PDCD1 (0.53) | ALDH1A1SMN1; SMN2LMNAUTS2RKMT2A | |
| SCHEMBL803259 | 0.81 | PDCD1 (0.53) | ALDH1A1SMN1; SMN2LMNAUTS2RKMT2A | |
| SCHEMBL9500011 | 0.80 | FAAH (0.53) | SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL1788624 | 0.79 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2LMNATDP1MAPT | |
| SCHEMBL4386993 | 0.78 | SIGMAR1 (0.46) | ALDH1A1SMN1; SMN2LMNATDP1ALPG | |
| SCHEMBL14547167 | 0.78 | SIGMAR1 (0.46) | ALDH1A1SMN1; SMN2LMNATDP1ALPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354655-B1 | 1-PHENYL-1-PROPANOL DERIVATIVES | CHISSO CORPORATION (JP) | 1993-04-07 | — | — | EP | disclosed |
| US-5076947-A | Optically active; free from temperature dependence | CHISSO CORPORATION (JP) | 1991-12-31 | — | — | US | disclosed |
| EP-0354655-A2 | 1-Phenyl-1-propanol derivatives | CHISSO CORPORATION (JP) | 1990-02-14 | — | — | EP | disclosed |