Sugi Predict

Sugi Predict / Compounds / SCHEMBL949937

SCHEMBL949937

SCHEMBL949937

CCCC(=O)OCC(O)CO[NH]

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.50
▸ DUSP3 P51452 1/20 0.50
▸ MEN1 O00255 1/20 0.50
▸ KMT2A Q03164 1/20 0.50
▸ LMNA P02545 1/20 0.50
▸ LPAR1 Q92633 7/20 0.47
▸ ENPP2 Q13822 6/20 0.47
▸ LPAR4 Q99677 3/20 0.47
▸ LPAR5 Q9H1C0 3/20 0.47
▸ LPAR2 Q9HBW0 3/20 0.47
▸ LPAR3 Q9UBY5 3/20 0.47
▸ LPAR6 P43657 2/20 0.47
▸ MAPT P10636 1/20 0.44
▸ DGKA P23743 1/20 0.43
▸ ALDH1A1 P00352 1/20 0.41
▸ TRPV1 Q8NER1 2/20 0.41
▸ CES2 O00748 1/20 0.41
▸ FAAH O00519 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3031373 0.90 KDM4E (0.58) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL3212267 0.84 KDM4E (0.41) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL13741499 0.82 KDM4E (0.51) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL949586 0.82 KDM4E (0.51) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL9005715 0.82 LMNA (0.55) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL16248464 0.81 KDM4E (0.50) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL988733 0.81 KDM4E (0.50) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL5610778 0.80 KDM4E (0.73) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL5610802 0.80 KDM4E (0.73) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL68553 0.80 KDM4E (0.73) KDM4EDUSP3MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1713786-B1 1-(AZOLIN-2-YL) AMINO-1,2-DIPHENYLETHANE COMPOUNDS FOR COMBATTING INSECTS, ARACHNIDS AND NEMATODES BASF SE (DE) 2012-08-08 — — EP disclosed
EP-1960369-B1 INDANYL-AND TETRAHYDRONAPHTHYL-AMINO-AZOLINE COMPOUNDS FOR COMBATING ANIMAL PESTS BASF SE (DE) 2012-01-11 — — EP disclosed
US-7981437-B2 Indanyl- and tetrahydronaphthyl-amino-azoline compounds for combating animal pests BASF SE (DE) 2011-07-19 — — US disclosed
US-7871960-B2 1-(Imidazolin-2-yl)amino-1,2-diphenylethane compounds for combating animal pests BASF SE (DE) 2011-01-18 — — US disclosed
EP-1888533-B1 1-(IMIDAZOLIN-2-YL)AMINO-1,2-DIPHENYLETHANE COMPOUNDS FOR COMBATING ANIMAL PESTS BASF SE (DE) 2010-12-15 — — EP disclosed
US-7674827-B2 Indanyl- and tetrahydronaphtyl-amino-thiourea compounds for combating animal pests BASF SE (DE) 2010-03-09 — — US disclosed
WO-2010021897-A1 NUCLEOSIDIC PHOSPHORAMIDITE CRYSTALLINE MATERIAL AND A PROCESS FOR PURIFYING THE SAME MERCK SHARP & DOHME CORP. (US) 2010-02-25 — — WO disclosed
US-7655600-B2 4,5-Dihydro-4-methyloxazol-2-yl)-[2-(3-chloro-phenyl)-1-phenyl-ethyl]-amine; 1-[1-(4-Chlorophenyl)-2-phenyl-ethyl]-(4,5-dihydrothiazol-2-yl)-amine; animal pests; agriculture; broad activity spectrum against difficult to control insects etc. BASF AKTIENGESELLSCHAFT (DE) 2010-02-02 — — US disclosed
WO-2009153238-A1 AMINOTHIAZOLINE COMPOUNDS FOR COMBATING INSECTS, ARACHNIDS AND NEMATODES BASF SE (DE) 2009-12-23 — — WO disclosed
US-20090075819-A1 Indanyl- and Tetrahydronaphtyl-amino-thiourea Compounds for Combating Animal Pests BASF SE (DE) 2009-03-19 — — US disclosed
EP-1890541-A2 1-(1,2-DIPHENYL-ETHYL)-3-(2-HYDROXYETHYL)-THIOUREA COMPOUNDS FOR COMBATING ANIMAL PESTS BASF AKTIENGESELLSCHAFT (DE) 2008-02-27 — — EP disclosed
EP-1888533-A1 1-(IMIDAZOLIN-2-YL)AMINO-1,2-DIPHENYLETHANE COMPOUNDS FOR COMBATING ANIMAL PESTS BASF AKTIENGESELLSCHAFT (DE) 2008-02-20 — — EP disclosed
WO-2007071585-A1 PESTCIDAL COMPOSITIONS BASF SE (DE) 2007-06-28 — — WO disclosed
US-20070149582-A1 1-(Azolin-2-yl)amino-1,2-diphenylethane compounds for combating insects, arachnids and nematodes BASF AKTIENGESELLSCHAFT (DE) 2007-06-28 — — US disclosed
WO-2007060120-A1 INDANYL-AND TETRAHYDRONAPHTYL-AMINO-THIOUREA COMPOUNDS FOR COMBATING ANIMAL PESTS BASF SE (DE) 2007-05-31 — — WO disclosed
WO-2007060121-A1 INDANYL-AND TETRAHYDRONAPHTHYL-AMINO-AZOLINE COMPOUNDS FOR COMBATING ANIMAL PESTS BASF SE (DE) 2007-05-31 — — WO disclosed
WO-2006125745-A2 1-(1,2-DIPHENYL-ETHYL)-3-(2-HYDROXYETHYL)-THIOUREA COMPOUNDS FOR COMBATING ANIMAL PESTS BASF AKTIENGESELLSCHAFT (DE) 2006-11-30 — — WO disclosed
WO-2006125748-A1 1-(IMIDAZOLIN-2-YL)AMINO-1,2-DIPHENYLETHANE COMPOUNDS FOR COMBATING ANIMAL PESTS BASF AKTIENGESELLSCHAFT (DE) 2006-11-30 — — WO disclosed
EP-1713786-A1 1-(AZOLIN-2-YL) AMINO-1,2-DIPHENYLETHANE COMPOUNDS FOR COMBATTING INSECTS, ARACHNIDS AND NEMATODES BASF AKTIENGESELLSCHAFT (DE) 2006-10-25 — — EP disclosed
WO-2005063724-A1 1-(AZOLIN-2-YL) AMINO-1,2-DIPHENYLETHANE COMPOUNDS FOR COMBATTING INSECTS, ARACHNIDS AND NEMATODES BASF AKTIENGESELLSCHAFT (DE) 2005-07-14 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070149582-A1 1-(Azolin-2-yl)amino-1,2-diphenylethane compounds for combating insects, arachnids and nematodes ANXA1, ANTXR2, ANXA2 KDM4E 2567/4885DUSP3 3791/4885MEN1 1710/4885
US-20090075819-A1 Indanyl- and Tetrahydronaphtyl-amino-thiourea Compounds for Combating Animal Pests AHCYL1, AHCY, TST KDM4E 3577/4885DUSP3 4547/4885MEN1 2068/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.