Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 6/20 | 0.49 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.49 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.49 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.49 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.49 |
| ▸ | LPAR6 | P43657 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | DGKA | P23743 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3031373 | 0.92 | KDM4E (0.58) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL13741499 | 0.84 | KDM4E (0.51) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL9005715 | 0.83 | LMNA (0.55) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL3208511 | 0.83 | KDM4E (0.42) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL949937 | 0.82 | KDM4E (0.50) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL988733 | 0.82 | KDM4E (0.50) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL15324674 | 0.82 | KDM4E (0.50) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL16248464 | 0.82 | KDM4E (0.50) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL5610778 | 0.82 | KDM4E (0.73) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL68553 | 0.82 | KDM4E (0.73) | KDM4EDUSP3MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713786-B1 | 1-(AZOLIN-2-YL) AMINO-1,2-DIPHENYLETHANE COMPOUNDS FOR COMBATTING INSECTS, ARACHNIDS AND NEMATODES | BASF SE (DE) | 2012-08-08 | — | — | EP | disclosed |
| EP-1960369-B1 | INDANYL-AND TETRAHYDRONAPHTHYL-AMINO-AZOLINE COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2012-01-11 | — | — | EP | disclosed |
| US-7981437-B2 | Indanyl- and tetrahydronaphthyl-amino-azoline compounds for combating animal pests | BASF SE (DE) | 2011-07-19 | — | — | US | disclosed |
| US-7871960-B2 | 1-(Imidazolin-2-yl)amino-1,2-diphenylethane compounds for combating animal pests | BASF SE (DE) | 2011-01-18 | — | — | US | disclosed |
| EP-1888533-B1 | 1-(IMIDAZOLIN-2-YL)AMINO-1,2-DIPHENYLETHANE COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2010-12-15 | — | — | EP | disclosed |
| US-7674827-B2 | Indanyl- and tetrahydronaphtyl-amino-thiourea compounds for combating animal pests | BASF SE (DE) | 2010-03-09 | — | — | US | disclosed |
| US-7655600-B2 | 4,5-Dihydro-4-methyloxazol-2-yl)-[2-(3-chloro-phenyl)-1-phenyl-ethyl]-amine; 1-[1-(4-Chlorophenyl)-2-phenyl-ethyl]-(4,5-dihydrothiazol-2-yl)-amine; animal pests; agriculture; broad activity spectrum against difficult to control insects etc. | BASF AKTIENGESELLSCHAFT (DE) | 2010-02-02 | — | — | US | disclosed |
| WO-2009153238-A1 | AMINOTHIAZOLINE COMPOUNDS FOR COMBATING INSECTS, ARACHNIDS AND NEMATODES | BASF SE (DE) | 2009-12-23 | — | — | WO | disclosed |
| US-20090075819-A1 | Indanyl- and Tetrahydronaphtyl-amino-thiourea Compounds for Combating Animal Pests | BASF SE (DE) | 2009-03-19 | — | — | US | disclosed |
| US-20080312085-A1 | Pesticidal Compositions | BASF SE (DE) | 2008-12-18 | — | — | US | disclosed |
| EP-1890541-A2 | 1-(1,2-DIPHENYL-ETHYL)-3-(2-HYDROXYETHYL)-THIOUREA COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF AKTIENGESELLSCHAFT (DE) | 2008-02-27 | — | — | EP | disclosed |
| EP-1888533-A1 | 1-(IMIDAZOLIN-2-YL)AMINO-1,2-DIPHENYLETHANE COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF AKTIENGESELLSCHAFT (DE) | 2008-02-20 | — | — | EP | disclosed |
| WO-2007071585-A1 | PESTCIDAL COMPOSITIONS | BASF SE (DE) | 2007-06-28 | — | — | WO | disclosed |
| US-20070149582-A1 | 1-(Azolin-2-yl)amino-1,2-diphenylethane compounds for combating insects, arachnids and nematodes | BASF AKTIENGESELLSCHAFT (DE) | 2007-06-28 | — | — | US | disclosed |
| WO-2007060121-A1 | INDANYL-AND TETRAHYDRONAPHTHYL-AMINO-AZOLINE COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2007-05-31 | — | — | WO | disclosed |
| WO-2007060120-A1 | INDANYL-AND TETRAHYDRONAPHTYL-AMINO-THIOUREA COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2007-05-31 | — | — | WO | disclosed |
| WO-2006125745-A2 | 1-(1,2-DIPHENYL-ETHYL)-3-(2-HYDROXYETHYL)-THIOUREA COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF AKTIENGESELLSCHAFT (DE) | 2006-11-30 | — | — | WO | disclosed |
| WO-2006125748-A1 | 1-(IMIDAZOLIN-2-YL)AMINO-1,2-DIPHENYLETHANE COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF AKTIENGESELLSCHAFT (DE) | 2006-11-30 | — | — | WO | disclosed |
| EP-1713786-A1 | 1-(AZOLIN-2-YL) AMINO-1,2-DIPHENYLETHANE COMPOUNDS FOR COMBATTING INSECTS, ARACHNIDS AND NEMATODES | BASF AKTIENGESELLSCHAFT (DE) | 2006-10-25 | — | — | EP | disclosed |
| WO-2005063724-A1 | 1-(AZOLIN-2-YL) AMINO-1,2-DIPHENYLETHANE COMPOUNDS FOR COMBATTING INSECTS, ARACHNIDS AND NEMATODES | BASF AKTIENGESELLSCHAFT (DE) | 2005-07-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149582-A1 | 1-(Azolin-2-yl)amino-1,2-diphenylethane compounds for combating insects, arachnids and nematodes | ANXA1, ANTXR2, ANXA2 | KDM4E 2567/4885DUSP3 3791/4885MEN1 1710/4885 |
| US-20090075819-A1 | Indanyl- and Tetrahydronaphtyl-amino-thiourea Compounds for Combating Animal Pests | AHCYL1, AHCY, TST | KDM4E 3577/4885DUSP3 4547/4885MEN1 2068/4885 |
| US-20080312085-A1 | Pesticidal Compositions | ANXA1, PRDX1, PRDX2 | KDM4E 2024/4885DUSP3 4414/4885MEN1 1132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.