Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9795454 | 0.84 | DRD2 (0.31) | ALDH1A1L3MBTL1SMN1; SMN2DRD2 | |
| SCHEMBL9499613 | 0.84 | DRD2 (0.31) | ALDH1A1L3MBTL1SMN1; SMN2DRD2 | |
| SCHEMBL9795380 | 0.82 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL9795309 | 0.81 | HSD11B1 (0.39) | HSD11B1ALDH1A1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL9499509 | 0.80 | SMYD3 (0.42) | ALDH1A1L3MBTL1SMN1; SMN2SMYD3 | |
| SCHEMBL9795275 | 0.80 | SMYD3 (0.42) | ALDH1A1L3MBTL1SMN1; SMN2SMYD3 | |
| SCHEMBL9499579 | 0.80 | SMYD3 (0.42) | ALDH1A1L3MBTL1SMN1; SMN2SMYD3 | |
| SCHEMBL9795077 | 0.78 | L3MBTL1 (0.35) | ALDH1A1L3MBTL1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL7816311 | 0.78 | DRD2 (0.46) | L3MBTL1KMT2ADRD2 | |
| SCHEMBL9498643 | 0.77 | KMT2A (0.40) | ALDH1A1L3MBTL1SMN1; SMN2LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037849-A | For treatment of heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1991-08-06 | — | — | US | disclosed |