Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 2/20 | 0.33 |
| ▸ | FURIN | P09958 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.31 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.31 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.31 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.31 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9498019 | 0.79 | TEAD4 (0.45) | HPGDMAPTRAB9AMMP13SMN1; SMN2 | |
| SCHEMBL5820050 | 0.78 | HPGD (0.58) | HPGDMAPTRAB9AFURINMMP13 | |
| SCHEMBL9495514 | 0.76 | SRD5A2 (0.55) | HPGDTSHRHTTPARP10KMT2A | |
| SCHEMBL9500742 | 0.76 | CA1 (0.55) | MAPTRAB9ASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL9496376 | 0.75 | CA1 (0.48) | MAPTRAB9AALDH1A1PARP10KMT2A | |
| SCHEMBL9775359 | 0.73 | SRD5A2 (0.40) | HPGDSMN1; SMN2ALDH1A1HTTPARP10 | |
| SCHEMBL9496291 | 0.72 | HSPB1 (0.39) | MAPTALDH1A1HTTKMT2A | |
| SCHEMBL9496161 | 0.71 | KMT2A (0.54) | MAPTSMN1; SMN2ALDH1A1TSHRHTT | |
| SCHEMBL19402993 | 0.71 | PARP10 (0.53) | HPGDMAPTRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9498280 | 0.71 | MAPT (0.45) | MAPTRAB9AALDH1A1TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0343441-B1 | FLUORINATED BIS-ARYLOXY-SUBSTITUTED ALKENES, METHOD FOR THEIR PRODUCTION AN THEIR APPLICATION | BAYER AG (DE) | 1993-03-24 | — | — | EP | disclosed |
| US-4990633-A | Used as insulating agents | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-05 | — | — | US | disclosed |
| EP-0343441-A2 | Fluorinated bis-aryloxy-substituted alkenes, method for their production an their application | BAYER AG (DE) | 1989-11-29 | — | — | EP | disclosed |