Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD4 | Q15561 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9495938 | 0.83 | HSD17B10 (0.55) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL9496376 | 0.83 | CA1 (0.48) | ALDH1A1TDP1MEN1KMT2AMAPT | |
| SCHEMBL9496291 | 0.80 | HSPB1 (0.39) | ALDH1A1TDP1MEN1KMT2AMAPT | |
| SCHEMBL9499643 | 0.79 | HPGD (0.38) | ALDH1A1KMT2AMAPTHTTSMN1; SMN2 | |
| SCHEMBL9497883 | 0.78 | ALDH1A1 (0.54) | TEAD4ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL9498280 | 0.78 | MAPT (0.45) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL9500512 | 0.78 | MAOA (0.45) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL9498861 | 0.78 | HAO1 (0.41) | ALDH1A1TDP1MEN1KMT2AMAPT | |
| SCHEMBL9364922 | 0.77 | LTA4H (0.50) | KMT2AMAPTTSHRCA1CA2 | |
| SCHEMBL9496753 | 0.74 | PARP15 (0.43) | ALDH1A1MEN1KMT2APOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0343441-B1 | FLUORINATED BIS-ARYLOXY-SUBSTITUTED ALKENES, METHOD FOR THEIR PRODUCTION AN THEIR APPLICATION | BAYER AG (DE) | 1993-03-24 | — | — | EP | disclosed |
| US-4990633-A | Used as insulating agents | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-05 | — | — | US | disclosed |
| EP-0343441-A2 | Fluorinated bis-aryloxy-substituted alkenes, method for their production an their application | BAYER AG (DE) | 1989-11-29 | — | — | EP | disclosed |