Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | LTA4H | P09960 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9496954 | 0.81 | MAPT (0.47) | MAPTSRD5A2LMNAMEN1MAPK1 | |
| SCHEMBL9496291 | 0.80 | HSPB1 (0.39) | MAPTLMNAMEN1MAPK1KMT2A | |
| SCHEMBL9498019 | 0.78 | TEAD4 (0.45) | MAPTLMNAMEN1RAB9AKMT2A | |
| SCHEMBL9497883 | 0.78 | ALDH1A1 (0.54) | MAPTMAOAMAOBMEN1MAPK1 | |
| SCHEMBL9500512 | 0.78 | MAOA (0.45) | MAPTMAOAMAOBCYP2A6LMNA | |
| SCHEMBL9364922 | 0.77 | LTA4H (0.50) | MAPTMAOAMAOBSRD5A2KMT2A | |
| SCHEMBL9496753 | 0.74 | PARP15 (0.43) | MAPTMAOBCYP2A6LMNAMEN1 | |
| SCHEMBL9499720 | 0.74 | ALDH1A1 (0.46) | MAPTCYP2A6LMNAKMT2AALDH1A1 | |
| SCHEMBL9499679 | 0.74 | — | — | |
| SCHEMBL3843978 | 0.72 | MAPT (0.74) | MAPTMAOAMAOBSRD5A2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2025441-A | — | — | None | — | — | JP | disclosed |
| EP-0343441-B1 | FLUORINATED BIS-ARYLOXY-SUBSTITUTED ALKENES, METHOD FOR THEIR PRODUCTION AN THEIR APPLICATION | BAYER AG (DE) | 1993-03-24 | — | — | EP | disclosed |
| US-4990633-A | Used as insulating agents | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-05 | — | — | US | disclosed |
| JP-H0225441-A | FLUORINATED BISARYLOXY-SUBSTITUTED ALKENE AND ITS PREPARATION | BAYER AG | 1990-01-26 | — | — | JP | disclosed |
| EP-0343441-A2 | Fluorinated bis-aryloxy-substituted alkenes, method for their production an their application | BAYER AG (DE) | 1989-11-29 | — | — | EP | disclosed |