Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | CASP6 | P55212 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | HCAR3 | P49019 | 11/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9500729 | 0.88 | CASP6 (0.58) | POLBCASP6TSHRHCAR3MEN1 | |
| SCHEMBL3530451 | 0.84 | VCAM1 (0.71) | POLBCASP6TSHRHCAR3MEN1 | |
| SCHEMBL9185447 | 0.83 | CASP6 (0.64) | POLBCASP6TSHRHCAR3MEN1 | |
| SCHEMBL28909765 | 0.81 | POLB (0.62) | POLBCASP6TSHRHCAR3MEN1 | |
| SCHEMBL9183692 | 0.81 | POLB (0.62) | POLBCASP6TSHRHCAR3MEN1 | |
| SCHEMBL6003204 | 0.81 | POLB (0.62) | POLBCASP6TSHRHCAR3MEN1 | |
| SCHEMBL20572634 | 0.81 | POLB (0.62) | POLBCASP6TSHRHCAR3MEN1 | |
| SCHEMBL9658192 | 0.79 | POLB (0.56) | POLBCASP6TSHRHCAR3MEN1 | |
| SCHEMBL6899620 | 0.78 | MEN1 (0.69) | POLBCASP6TSHRHCAR3MEN1 | |
| SCHEMBL9658195 | 0.77 | POLB (0.56) | POLBCASP6TSHRHCAR3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0312922-B1 | OXETHYLSULFONYL-NITRO- OR -AMINO-BENZOIC ACIDS AND PROCESS FOR THEIR PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-02 | — | — | EP | disclosed |
| EP-0312922-A2 | Oxethylsulfonyl-nitro- or -amino-benzoic acids and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-04-26 | — | — | EP | disclosed |