Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 1/20 | 0.71 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | CASP6 | P55212 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | HCAR3 | P49019 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 6/20 | 0.56 |
| ▸ | THRA | P10827 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6450193 | 0.89 | VCAM1 (0.59) | VCAM1POLBCASP6TSHRHCAR3 | |
| SCHEMBL18113472 | 0.87 | CASP6 (0.62) | VCAM1POLBCASP6TSHRHCAR3 | |
| SCHEMBL9185447 | 0.85 | CASP6 (0.64) | VCAM1POLBCASP6TSHRHCAR3 | |
| SCHEMBL9499862 | 0.84 | POLB (0.59) | VCAM1POLBCASP6TSHRHCAR3 | |
| SCHEMBL9183692 | 0.84 | POLB (0.62) | VCAM1POLBCASP6TSHRHCAR3 | |
| SCHEMBL20572634 | 0.84 | POLB (0.62) | VCAM1POLBCASP6TSHRHCAR3 | |
| SCHEMBL28909765 | 0.84 | POLB (0.62) | VCAM1POLBCASP6TSHRHCAR3 | |
| SCHEMBL6003204 | 0.84 | POLB (0.62) | VCAM1POLBCASP6TSHRHCAR3 | |
| SCHEMBL9658192 | 0.82 | POLB (0.56) | VCAM1POLBCASP6TSHRHCAR3 | |
| SCHEMBL6899620 | 0.81 | MEN1 (0.69) | VCAM1POLBCASP6TSHRHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119059914-A | Method for preparing trifluoro benzoic acid derivative | 帕潘纳(北京)科技有限公司 | 2024-12-03 | — | — | CN | disclosed |
| EP-3222606-B1 | CARBOXYLIC ACID PREPARATION METHOD | ZHEJIANG ZHUJI UNITED CHEMICALS CO LTD (CN) | 2019-08-07 | — | — | EP | disclosed |
| US-10167246-B2 | Preparative method for carboxylic acids | ZHEJIANG ZHUJI UNITED CHEMICALS CO., LTD (CN) | 2019-01-01 | — | — | US | disclosed |
| US-20170369412-A1 | Preparative method for carboxylic acids | ZHEJIANG ZHUJI UNITED CHEMICALS CO., LTD | 2017-12-28 | — | — | US | disclosed |
| EP-3222606-A1 | CARBOXYLIC ACID PREPARATION METHOD | Zhejiang Zhuji United Chemicals Co., Ltd (CN) | 2017-09-27 | — | — | EP | disclosed |
| CN-105646120-A | Preparation method of carboxylic acid | 浙江省诸暨合力化学对外贸易有限公司 | 2016-06-08 | — | — | CN | disclosed |
| US-7709479-B1 | Quinazoline derivatives and their use as pharmaceuticals | ASTRAZENECA (SE) | 2010-05-04 | — | — | US | disclosed |
| US-20090118332-A1 | Therapeutic Agents - 551 | ASTRAZENECA AB (SE) | 2009-05-07 | — | — | US | disclosed |
| US-20090105305-A1 | Therapeutic Agents - 550 | ASTRAZENECA AB (SE) | 2009-04-23 | — | — | US | disclosed |
| US-7504410-B2 | Chk-, Pdk- and Akt-inhibitory pyrimidines, their production and use as pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 2009-03-17 | — | — | US | disclosed |
| US-5478820-A | Carbapenem deivatives; bactericides | ZENECA LTD. (GB) | 1995-12-26 | — | — | US | disclosed |
| EP-0579826-A1 | CARBAPENEMS CONTAINING A CARBOXY SUBSTITUTED PHENYL GROUP, PROCESSES FOR THEIR PREPARATION, INTERMEDIATES AND USE AS ANTIBIOTICS | ZENECA LIMITED (GB) | 1994-01-26 | — | — | EP | disclosed |
| CN-1079224-A | Antifungal compound | ZENECA LTD (GB) | 1993-12-08 | — | — | CN | disclosed |
| WO-1993015078-A1 | CARBAPENEMS CONTAINING A CARBOXY SUBSTITUTED PHENYL GROUP, PROCESSES FOR THEIR PREPARATION, INTERMEDIATES AND USE AS ANTIBIOTICS | ZENECA LIMITED (GB) | 1993-08-05 | — | — | WO | disclosed |
| US-4564623-A | HISTAMINE H2-ANTAGONISTS, ANTIULCER AGENTS | SHIONOGI & CO., LTD. (JP) | 1986-01-14 | — | — | US | disclosed |
| US-4482566-A | ANTIULCER AGENTS | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |
| EP-0023578-B1 | AMINOALKYLBENZENE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS | SHIONOGI & CO., LTD. (JP) | 1984-05-30 | — | — | EP | disclosed |
| US-4309433-A | TREATMENT OF PEPTIC ULCERS | SHIONOGI & CO., LTD. (JP) | 1982-01-05 | — | — | US | disclosed |
| EP-0023578-A1 | Aminoalkylbenzene derivatives, process for their preparation and pharmaceutical compositions | SHIONOGI & CO., LTD. (JP) | 1981-02-11 | — | — | EP | disclosed |
| US-4247597-A | Electroscopic carrier particles having a carboxylic acid surface treatment | PITNEY BOWES, INC. (US) | 1981-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105305-A1 | Therapeutic Agents - 550 | FABP4, GPR119, FASN | VCAM1 1433/4885POLB 2341/4885CASP6 1602/4885 |
| US-20170369412-A1 | Preparative method for carboxylic acids | CBR3, CBR1, QPCT | VCAM1 4453/4885POLB 1538/4885CASP6 618/4885 |
| US-10167246-B2 | Preparative method for carboxylic acids | CBR3, CBR1, QPCT | VCAM1 4453/4885POLB 1538/4885CASP6 618/4885 |
| US-20090118332-A1 | Therapeutic Agents - 551 | GPR119, FABP4, FASN | VCAM1 1132/4885POLB 2291/4885CASP6 2171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.