Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12610959 | 0.79 | TSHR (0.36) | ALDH1A1TSHR | |
| SCHEMBL9498044 | 0.78 | — | — | |
| SCHEMBL16908593 | 0.72 | — | — | |
| SCHEMBL19906360 | 0.72 | THRB (0.31) | ALDH1A1TSHR | |
| SCHEMBL2694075 | 0.72 | ALDH1A1 (0.31) | ALDH1A1LMNA | |
| SCHEMBL26328658 | 0.72 | — | — | |
| SCHEMBL27438786 | 0.72 | TSHR (0.42) | HCAR2ALDH1A1TSHRLMNA | |
| SCHEMBL8728537 | 0.71 | HCAR2 (0.37) | HCAR2ALDH1A1TSHRLMNA | |
| SCHEMBL5670479 | 0.69 | LMNA (0.38) | HCAR2ALDH1A1TSHRLMNA | |
| SCHEMBL891844 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272110-B1 | ERYTHROMYCIN A DERIVATIVES AND METHOD FOR THE PREPARATION OF THE SAME | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1993-04-07 | — | — | EP | disclosed |
| US-4990602-A | Bactericides | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1991-02-05 | — | — | US | disclosed |
| EP-0272110-A2 | Erythromycin a derivatives and method for the preparation of the same | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1988-06-22 | — | — | EP | disclosed |