Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | WRN | Q14191 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | VCP | P55072 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | FBP1 | P09467 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9500935 | 0.81 | ALDH1A1 (0.38) | GAAALDH1A1LMNAKMT2A | |
| SCHEMBL6450202 | 0.81 | RECQL (0.36) | NAAAGAARECQLALDH1A1KDM4E | |
| SCHEMBL7158605 | 0.74 | LMNA (0.43) | NAAAGAARECQLALDH1A1KDM4E | |
| SCHEMBL9499560 | 0.72 | LMNA (0.31) | LMNA | |
| SCHEMBL17176122 | 0.71 | NAAA (0.47) | NAAAGAARECQLHTTALDH1A1 | |
| SCHEMBL6792231 | 0.70 | NAAA (0.50) | NAAAGAAHTTALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL28279690 | 0.69 | NAAA (0.45) | NAAAGAARECQLHTTALDH1A1 | |
| SCHEMBL5396590 | 0.69 | NAAA (0.48) | NAAAGAAHTTALDH1A1KDM4E | |
| SCHEMBL8581054 | 0.69 | NAAA (0.48) | NAAAGAAHTTALDH1A1KDM4E | |
| SCHEMBL50301 | 0.68 | NAAA (0.64) | NAAAGAAHTTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0373759-B1 | COMPOUND, COMPOSITION, PROCESS AND USE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-06-09 | — | — | EP | claimed |
| EP-0373759-A1 | Compound, composition, process and use | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-06-20 | — | — | EP | claimed |
| EP-0373759-B1 | COMPOUND, COMPOSITION, PROCESS AND USE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-06-09 | — | — | EP | disclosed |
| US-5112871-A | ANTI-MICROBIAL BROMO-NITRO COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-05-12 | — | — | US | disclosed |
| EP-0373759-A1 | Compound, composition, process and use | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-06-20 | — | — | EP | disclosed |