Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.52 |
| ▸ | DRD3 | P35462 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9579386 | 0.92 | DRD2 (0.58) | DRD2DRD3ALDH1A1HSD17B10DRD4 | |
| SCHEMBL219349 | 0.87 | ALDH1A1 (0.61) | DRD2DRD3ALDH1A1HSD17B10DRD4 | |
| SCHEMBL6927912 | 0.81 | HTR1A (0.64) | DRD2DRD3HTR1AMAPTSLC6A2 | |
| Hydrochloric Acid SCHEMBL7302055 | 0.80 | LMNA (0.65) | DRD2DRD3HTR1AMAPTSLC6A2 | |
| SCHEMBL217093 | 0.78 | DRD2 (0.66) | DRD2DRD3ALDH1A1SMN1; SMN2HTR1A | |
| SCHEMBL27597995 | 0.77 | DRD2 (0.57) | DRD2DRD3ALDH1A1HSD17B10DRD4 | |
| SCHEMBL4750831 | 0.76 | FFAR4 (0.40) | ALDH1A1HSD17B10SMN1; SMN2MAPTKDM4E | |
| SCHEMBL7510093 | 0.76 | HTR1A (0.57) | DRD2ALDH1A1HTTHTR1AMAPT | |
| SCHEMBL4724465 | 0.76 | DRD2 (0.44) | DRD2DRD3ALDH1A1HSD17B10DRD4 | |
| SCHEMBL9332845 | 0.75 | DRD2 (0.67) | DRD2DRD3ALDH1A1HSD17B10DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273444-B1 | USE OF CARBOXAMIDE COMPOUNDS FOR THE PREPARATION OF A MEDICAMENT FOR TREATING HYPERLIPIDEMIA | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1993-05-05 | — | — | EP | disclosed |
| US-5081112-A | Administering an aryl phosphonate carboxamide | OTSUKA PHARMACEUTICAL FACTORY INC. (JP) | 1992-01-14 | — | — | US | disclosed |