Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 2/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | FABP3 | P05413 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27731060 | 0.84 | KIF11 (0.42) | KMOERAP1KIF11SLC22A12AR | |
| SCHEMBL9501440 | 0.81 | KMO (0.43) | KMORAB9AERAP1KIF11FABP4 | |
| SCHEMBL27731061 | 0.76 | KMO (0.44) | KMOAR | |
| SCHEMBL4251283 | 0.74 | KMO (0.46) | KMORAB9AFABP4KITKDR | |
| SCHEMBL8659975 | 0.74 | SLC22A12 (0.42) | KIF11SLC22A12F10 | |
| SCHEMBL8660169 | 0.73 | ALOX5AP (0.48) | KIF11SLC22A12F10 | |
| SCHEMBL16608991 | 0.71 | KMO (0.54) | KMOKIF11RORCAR | |
| SCHEMBL8663462 | 0.71 | ALOX5AP (0.46) | KIF11SLC22A12 | |
| SCHEMBL8577408 | 0.70 | CA12 (0.47) | MEN1ALDH1A1KMT2AKIF11CYP2C9 | |
| SCHEMBL31541734 | 0.69 | RAB9A (0.57) | RAB9AMEN1KMT2AFABP4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5210290-A | NMR diagnostic aid | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-05-11 | — | — | US | disclosed |