Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.43 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.42 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 3/20 | 0.37 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | FLT3 | P36888 | 2/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | FABP3 | P05413 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4251283 | 0.82 | KMO (0.46) | KMOACMSDRAB9ARIPK1FABP4 | |
| SCHEMBL9501436 | 0.81 | KMO (0.43) | KMOERAP1KIF11RAB9ARORC | |
| SCHEMBL29226029 | 0.75 | HNF4A (0.56) | ACMSDRAB9AALOX15FABP4FABP3 | |
| SCHEMBL30153392 | 0.75 | HNF4A (0.56) | ACMSDRAB9AALOX15FABP4FABP3 | |
| SCHEMBL31583298 | 0.75 | BCAT2 (0.51) | KMORAB9ARIPK1RORC | |
| SCHEMBL6728905 | 0.74 | PTGS2 (0.66) | KIF11PTGS1PTGS2 | |
| SCHEMBL8660169 | 0.73 | ALOX5AP (0.48) | KIF11PTGS1PTGS2 | |
| SCHEMBL3860114 | 0.72 | ALB (0.53) | RAB9AALOX15FABP4DHODH | |
| SCHEMBL16608991 | 0.71 | KMO (0.54) | KMOKIF11RORC | |
| SCHEMBL8663462 | 0.71 | ALOX5AP (0.46) | KIF11PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5210290-A | NMR diagnostic aid | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-05-11 | — | — | US | disclosed |