Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | LTA4H | P09960 | 4/20 | 0.42 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9503547 | 0.95 | MAOA (0.45) | MAOAMAOBLTA4HARALDH1A1 | |
| SCHEMBL9503139 | 0.90 | MAOA (0.47) | MAOAMAOBLTA4HARALDH1A1 | |
| SCHEMBL9503489 | 0.86 | LTA4H (0.43) | MAOAMAOBLTA4HARALDH1A1 | |
| SCHEMBL9501765 | 0.83 | SLC6A4 (0.44) | MAOAMAOBLTA4HALDH1A1RAB9A | |
| SCHEMBL9503567 | 0.81 | LTA4H (0.63) | LTA4HALDH1A1TSHRHPGDKDM4E | |
| SCHEMBL9503541 | 0.78 | LTA4H (0.66) | LTA4HTSHRHPGDRAB9ANPC1 | |
| SCHEMBL9502103 | 0.78 | LTA4H (0.44) | LTA4HALDH1A1HPGDKDM4ERAB9A | |
| SCHEMBL10731219 | 0.77 | ALDH1A1 (0.40) | MAOAMAOBLTA4HALDH1A1KDM4E | |
| SCHEMBL10731318 | 0.77 | ALDH1A1 (0.40) | MAOAMAOBLTA4HALDH1A1KDM4E | |
| SCHEMBL13397915 | 0.77 | CA12 (0.50) | MAOAMAOBLTA4HARALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0186190-B1 | BENZIMIDAZOLE DERIVATIVES, AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-05-26 | — | — | EP | disclosed |
| EP-0132606-B1 | BENZIMIDAZOLE DERIVATIVES, AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-10-07 | — | — | EP | disclosed |
| US-4663339-A | Acaricidal and insecticidal substituted 1-phenylalkylbenzimidazoles | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-05-05 | — | — | US | disclosed |
| US-4612323-A | Insecticidal and acaricidal derivatives of 1-benzylbenzimidazole | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-09-16 | — | — | US | disclosed |
| EP-0186190-A2 | Benzimidazole derivatives, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-07-02 | — | — | EP | disclosed |
| EP-0132606-A1 | Benzimidazole derivatives, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-02-13 | — | — | EP | disclosed |