Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.51 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.51 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL608302 | 0.80 | MAPT (0.63) | PKMLMNAGAAALDH1A1KMT2A | |
| SCHEMBL9501073 | 0.79 | GAA (0.59) | PKMLMNAGAAALDH1A1KMT2A | |
| SCHEMBL12726868 | 0.79 | CYP2D6 (0.76) | PKMLMNAGAAALDH1A1KMT2A | |
| SCHEMBL10974777 | 0.77 | POLB (0.62) | PKMLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL1461195 | 0.76 | PKM (0.70) | PKMGAAALDH1A1CHRNB2CHRNB4 | |
| SCHEMBL735657 | 0.76 | POLB (0.80) | PKMLMNAGAAALDH1A1CYP2D6 | |
| SCHEMBL3830424 | 0.76 | POLB (0.80) | PKMLMNAGAAALDH1A1CYP2D6 | |
| SCHEMBL7122592 | 0.76 | POLB (0.80) | PKMLMNAGAAALDH1A1CYP2D6 | |
| SCHEMBL7131206 | 0.75 | KDM4E (0.78) | LMNAGAAALDH1A1CYP2D6POLB | |
| SCHEMBL7269243 | 0.75 | KDM4E (0.66) | LMNAGAAALDH1A1CYP2D6POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0330910-B1 | PROPANE DERIVATIVES | KOWA COMPANY, LTD. (JP) | 1993-05-12 | — | — | EP | disclosed |
| US-4960883-A | Cardiovascular disorders | KOWA COMPANY, LTD. (JP) | 1990-10-02 | — | — | US | disclosed |
| EP-0330910-A1 | Propane derivatives | KOWA COMPANY, LTD. (JP) | 1989-09-06 | — | — | EP | disclosed |