Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12726868 | 0.81 | CYP2D6 (0.76) | GAAPKMLMNAALDH1A1KMT2A | |
| SCHEMBL9502114 | 0.79 | PKM (0.57) | GAAPKMLMNAALDH1A1KMT2A | |
| SCHEMBL1350184 | 0.77 | MEN1 (0.73) | GAAPKMLMNAALDH1A1KMT2A | |
| SCHEMBL1350186 | 0.77 | MEN1 (0.73) | GAAPKMLMNAALDH1A1KMT2A | |
| SCHEMBL9502176 | 0.77 | KDM4E (0.48) | GAAPKMLMNAALDH1A1KMT2A | |
| SCHEMBL6432243 | 0.77 | SMN1; SMN2 (0.47) | GAALMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL608302 | 0.74 | MAPT (0.63) | GAAPKMLMNAALDH1A1KMT2A | |
| SCHEMBL9504097 | 0.74 | KDM4E (0.45) | GAAPKMLMNAALDH1A1KMT2A | |
| SCHEMBL1353299 | 0.74 | MEN1 (0.68) | GAAPKMLMNAALDH1A1KMT2A | |
| SCHEMBL10386225 | 0.73 | ALDH1A1 (0.45) | GAAPKMLMNAALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0330910-B1 | PROPANE DERIVATIVES | KOWA COMPANY, LTD. (JP) | 1993-05-12 | — | — | EP | disclosed |
| US-4960883-A | Cardiovascular disorders | KOWA COMPANY, LTD. (JP) | 1990-10-02 | — | — | US | disclosed |
| EP-0330910-A1 | Propane derivatives | KOWA COMPANY, LTD. (JP) | 1989-09-06 | — | — | EP | disclosed |