Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.40 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.40 |
| ▸ | KDM6B | O15054 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.39 |
| ▸ | KDM3B | Q7LBC6 | 1/20 | 0.39 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9429289 | 0.74 | CYSLTR2 (0.51) | LTB4RFAAHARMRGPRX4CYSLTR2 | |
| SCHEMBL9504626 | 0.69 | NPC1 (0.43) | FAAHPLA2G4BPLA2G4AKDM6BKDM4A | |
| SCHEMBL9501802 | 0.68 | CYSLTR2 (0.46) | FAAHCES1CYSLTR2CYSLTR1RXFP1 | |
| SCHEMBL9427841 | 0.67 | CYSLTR2 (0.66) | LTB4RFAAHARMRGPRX4CYSLTR2 | |
| SCHEMBL9427834 | 0.67 | CYSLTR2 (0.66) | LTB4RFAAHARMRGPRX4CYSLTR2 | |
| SCHEMBL9505492 | 0.67 | NPC1 (0.44) | FAAHKDM6BKDM4AKDM4DKDM3B | |
| SCHEMBL9501799 | 0.66 | KDM4E (0.43) | PLA2G4BPLA2G4AKDM6BKDM4AKDM4D | |
| SCHEMBL315037 | 0.66 | SMN1; SMN2 (0.68) | RAB9ASMN1; SMN2HTTACMSDNPC1 | |
| SCHEMBL9501780 | 0.66 | PLA2G7 (0.44) | KDM6BKDM4AKDM4DKDM3BHIF1AN | |
| SCHEMBL184313 | 0.65 | FOLH1 (0.54) | RAB9ASMN1; SMN2HTTARMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548291-A1 | PYRIDYLTHIO OR PYRIDYLOXY ALKANOIC ACIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-06-30 | — | — | EP | disclosed |
| WO-1992005156-A1 | PYRIDYLTHIO OR PYRIDYLOXY ALKANOIC ACIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1992-04-02 | — | — | WO | disclosed |